283-60-3Relevant articles and documents
1-Hydrosilatrane: A Locomotive for Efficient Ketone Reductions
Varjosaari, Sami E.,Skrypai, Vladislav,Suating, Paolo,Hurley, Joseph J. M.,Gilbert, Thomas M.,Adler, Marc J.
supporting information, p. 229 - 232 (2017/01/24)
An efficient method for the reduction of ketones with 1-hydrosilatrane is described. In the presence of a Lewis base activator, the resulting secondary alcohols are rapidly formed in good to excellent yields (20 examples, 71–99 % yields). The relative bulkiness of 1-hydrosilatrane also enables the diastereoselective reduction of (–)-menthone to (+)-neomenthol, and the use of a chiral alkoxide activator can lead to the enantioselective reduction of prochiral ketones.
Tri-organotin silatrane derivatives and pesticidal compositions, fungicides or antifouling agents comprising said compounds as active ingredients
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, (2008/06/13)
A tri-organotin silatrane derivative represented by the general formula (I) STR1 wherein the R1 groups are identical or different and each represents an alkyl, cycloalkyl, aryl or aralkyl group, R2, R3 and R4 are identical or different and each represents a hydrogen atom or a lower alkyl group, and m is a number of 2 or 3. The tri-organotin silatrane derivatives of the formula (I) are prepared by subjecting a 1-mercaptoalkylsilatrane and a tri-organotin hydroxide or bis(tri-organotin) oxide to a dehydration reaction, or reacting a 1-mercaptoalkylsilatrane derivative with a tri-organotin halide in the presence of a dehydrohalogenation agent, or subjecting a trialkoxysilane and a trialkanolamine to an ester-interchange reaction in the presence of an alkaline catalyst. The tri-organotin silatrane derivatives of the formula (I) are useful for an agricultural-horticultural pesticide, an industrial fungicide, an epidemic-preventing insecticide or an antifouling agent.
Process for the production of 1-organylsilatranes and carbofunctional derivatives thereof
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, (2008/06/13)
A process for the production of 1-organylsilatranes and their carbofunctional derivatives of the general formula where R = --CH2 --CH2 -- or --CH(CH3)CH2- ; Z is a bivalent hydrocarbon radical; X = H, alkyl, aryl, F, Cl, Br, I, CF3, CN, NH2, SH, CNS, R1 M, (R2 O)2 P(O), R3 C(O)M, where R1 is alkyl, aryl, aralkyl or alkaryl; M = O or S; R2 is alkyl; and R3 is alkyl, aryl, RF (a fluorocarbon chain containing from 1 to 10 carbon atoms) or A-C6 H4 OCH2, where A is halogen, an alkyl group or an alkoxy group which comprises reacting triethanolamine or its derivatives of the general formula where R = --CH2-CH 2-- or --CH(CH3)CH2 --, with 1-organyltrialkoxysilanes of the general formula where R4 is alkyl; X = H, alkyl, aryl, I, Br, Cl, F, CF3, CN, NH2, SH, CNS, R1 M, (R2 O)2 P(O) or R3 C(O)M, where R1 is alkyl, aryl, aralkyl or alkaryl; M = O or S; R2 is alkyl; and R3 is alkyl, aryl, RF (a fluorocarbon chain containing from 1 to 10 carbon atoms) or A-C6 H4 OCH2, where A is halogen, an alkyl group or an alkoxy group, in the presence of a low-boiling polar organic solvent or a low-boiling polar organic solvent combined with an alkali catalyst, and subsequently recovering the desired product, and, the triethanolamine or its derivatives are initially admixed with said solvent, after which the 1-organyltrialkoxysilane is added to the reaction mixture.
