28302-62-7 Usage
Uses
Used in Pharmaceutical Research:
[(2R,3R,4R,5R)-5-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid is used as a research compound for exploring its potential biological activities and interactions with biological targets. Its unique structure may offer insights into novel mechanisms of action for drug development.
Used in Biochemical Research:
In the field of biochemical research, [(2R,3R,4R,5R)-5-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid is used as a tool to study its interactions with various biomolecules, potentially leading to the discovery of new biochemical pathways or targets for therapeutic intervention.
Used in Drug Development:
[(2R,3R,4R,5R)-5-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetra en-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid is used as a lead molecule in drug development, with its unique structure being investigated for potential therapeutic applications. Further research and testing are necessary to fully understand its properties and potential uses in creating new medications.
Used in Medicinal Chemistry:
In medicinal chemistry, [(2R,3R,4R,5R)-5-(5-amino-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid serves as a starting point for the design and synthesis of new drug candidates, leveraging its unique molecular features to create novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 28302-62-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,0 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28302-62:
(7*2)+(6*8)+(5*3)+(4*0)+(3*2)+(2*6)+(1*2)=97
97 % 10 = 7
So 28302-62-7 is a valid CAS Registry Number.
28302-62-7Relevant academic research and scientific papers
Variable-Temperature NMR Spectroscopy, Conformational Analysis, and Thermodynamic Parameters of Cyclic Adenosine 5′-Diphosphate Ribose Agonists and Antagonists
Saatori, Sarah-Marie,Perez, Tanner J.,Graham, Steven M.
, p. 2554 - 2569 (2018/03/09)
Cyclic adenosine 5′-diphosphate ribose (cADPR) is a ubiquitous Ca2+-releasing second messenger. Knowledge of its conformational landscape is an essential tool for unraveling the structure-activity relationship (SAR) in cADPR. Variable-temperature 1H NMR spectroscopy, in conjunction with PSEUROT and population analyses, allowed us to determine the conformations and thermodynamic parameters of the furanose rings, γ-bonds (C4′-C5′), and β-bonds (C5′-O5′) in the cADPR analogues 2′-deoxy-cADPR, 7-deaza-cADPR, and 8-bromo-cADPR. A significant finding was that, although the analogues are similar to each other and to cADPR itself in terms of overall conformation and population (ΔG°), there were subtle yet important differences in some of thermodynamic properties (ΔH°, ΔS°) associated with each of the conformational equilibria. These differences prompted us to propose a model for cADPR in which the interactions between the A2′-N3, A5″-N3, and H2-R5′ atoms serve to fine-tune the N-glycosidic torsion angles (χ).
7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production
-
, (2008/06/13)
Hydroxy, amino and sulfhydryl derivatives of 7-β-D-arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine, their corresponding esters and non-toxic pharmaceutically acceptable salts are produced by arabinofuranosylation of the requisite heterocycles with 2,3,5-tri-
