28311-22-0 Usage
Uses
Used in Chemical Industry:
2-Pyrolidinone, 4-(2-Chlorophenyl) is used as a solvent for its ability to dissolve a wide range of substances, facilitating various chemical reactions and processes in the industry.
Used in Polymer and Resin Manufacturing:
In this application industry, 2-Pyrolidinone, 4-(2-Chlorophenyl) is utilized as a solvent to aid in the production of polymers and resins, enhancing the manufacturing process due to its solubility and boiling properties.
Used in Pharmaceutical Production:
2-Pyrolidinone, 4-(2-Chlorophenyl) is employed as a solvent in the pharmaceutical sector, where its properties are leveraged to assist in the synthesis and formulation of various drugs.
It is crucial to handle 2-Pyrolidinone, 4-(2-Chlorophenyl) with care due to its potential health and environmental risks if mismanaged. Proper management and control measures should be implemented to mitigate any adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 28311-22-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,1 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28311-22:
(7*2)+(6*8)+(5*3)+(4*1)+(3*1)+(2*2)+(1*2)=90
90 % 10 = 0
So 28311-22-0 is a valid CAS Registry Number.
28311-22-0Relevant academic research and scientific papers
Efficient synthesis of β-aryl-γ-lactams and their resolution with (S)-Naproxen: Preparation of (R)- and (S)-Baclofen
Montoya-Balbás, Iris J.,Valentín-Guevara, Berenice,López-Mendoza, Estefanía,Linzaga-Elizalde, Irma,Ordo?ez, Mario,Román-Bravo, Perla
, p. 22028 - 22043 (2016/01/25)
An efficient synthesis of enantiomerically-pure β-aryl-γ-lactams is described. The principal feature of this synthesis is the practical resolution of β-aryl-γ-lactams with (S)-Naproxen. The procedure is based on the Michael addition of nitromethane to benzylidenemalonates, which was easily obtained, followed by the reduction of the γ-nitroester in the presence of Raney nickel and the subsequent saponification/decarboxylation reaction. The utility of this methodology was highlighted by the preparation of enantiomerically-pure (R)- and (S)-Baclofen hydrochloride.
