28313-69-1Relevant academic research and scientific papers
Studies towards the synthesis of Fipronil analogues: Improved decarboxylation of α-hydrazonoacid derivatives
Ancel,El Ka?m,Gadras,Grimaud,Jana
, p. 8319 - 8321 (2002)
The Mannich reaction of hydrazones coupled with a [4+1] cycloaddition with isocyanides has been used for the synthesis of aminopyrazole analogues of Fipronil. The starting cyanohydrazone was prepared with new experimental conditions for efficient diazonium coupling in fluorinated solvents followed by a new sodium cyanide catalysed decarboxylation.
