2832-45-3

Basic information

• Product Name: Sodium 1-hexanesulfonate
• Synonyms: 1-HEXANESULFONATE, SODIUM;1-HEXANESULFONATE, SODIUM SALT;1-HEXANESULFONIC ACID SODIUM SALT;1-HEXANESULPHONATE, SODIUM SALT;1-HEXANESULPHONIC ACID SODIUM SALT;IPC(TM) B6;IPC-ALKS-6;HEXYL SODIUM SULFONATE
• CAS NO: 2832-45-3
• Molecular Formula: C₆H₁₃O₃S*Na
• Molecular Weight: 188.22
• EINECS: 220-601-3
• Product Categories: Alkyl Aryl Sodium Sulfonate Series;Analytical Chemistry;HPLC Ion-Pair Reagents for Basic Samples;Ion-Pair Reagents for HPLC;Ion-pair Reagents
• Mol File: 2832-45-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: White/Liquid
• Density: 1.017 g/cm
• Storage Temp.: Store at +5°C to +30°C.
• Solubility: H2O: soluble0.1M at 20°C, clear, colorless
• Water Solubility: Soluble in water.
• BRN: 3727014
• CAS DataBase Reference: Sodium 1-hexanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 1-hexanesulfonate(2832-45-3)
• EPA Substance Registry System: Sodium 1-hexanesulfonate(2832-45-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36/37/39-27-24/25
• WGK Germany: 3
• F: 8-10
• TSCA: Yes
• Hazardous Substances Data: 2832-45-3(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline solid

Uses

Different sources of media describe the Uses of 2832-45-3 differently. You can refer to the following data:
1. suzuki reaction
2. Sodium 1-hexanesulfonate is used as a base in the organic coupling reactions such as Suzuki coupling reactions. It is used as an ion pairing reagent for HPLC and involved in the analysis of peptides and proteins. It is also used in high performance capillary electrophoresis analysis of peptides.

General Description

Concentrate for 6x1 L ready-to-use solution. Dilute contents of one ampule (~0.3 M) to 1 L with HPLC grade water to obtain a 0.005 M eluent solution.

InChI:InChI=1/C6H14O3S.Na/c1-2-3-4-5-6-10(7,8)9;/h2-6H2,1H3,(H,7,8,9);/q;+1/p-1/rC6H13NaO3S/c1-2-3-4-5-6-11(8,9)10-7/h2-6H2,1H3

Upstream product

• 83633-54-9 Sodium 2-chlorohexane-1-sulfonate 
• 83633-52-7 Methyl 2-chlorohexane-1-sulfonate 
• 83633-56-1 2-Chlorohexane-1-sulfonyl chloride 
• 83633-58-3 trans-1-Hexene-1-sulfonyl chloride 
• 592-41-6 1-hexene 
• 111-25-1 1-bromo-hexane 
• 83633-60-7 Sodium trans-1-hexene-1-sulfonate 

Downstream Products

• 1293990-64-3 2-phenyl-9-tetradecyl-benzo[8,9]quinolizino[4,5,6,7-fed]phenanthridinylium hexanesulfonate 
• 65269-96-7 hexane-1-sulfonyl fluoride 
• 106273-92-1 Hexyl-sulfonsaeure-<4-nitro-phenylester> 
• 14532-24-2 1-hexanesulfonyl chloride 

Relevant articles and documents

N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing

A series of 11 N-sulfonyl homoserine lactones has been synthesised. Some of them were found to competitively inhibit the action of 3-oxohexanoyl-L- homoserine lactone, the natural inducer of bioluminescence in the bacterium Vibrio fischeri. Molecular modeling suggests a possible explanation based on the prevention of structural rearrangements necessary for the formation of the active dimer of LuxR.

One-Step Synthesis of Esters of Aliphatic β-Chloro Sulfonic Acids. Their Sequential Conversion to Other Sulfonic Acid Derivatives

A one-step synthesis of methyl 2-chlorohexane-1- and 2-chlorooctane-1-sulfonate by the novel free-radical addition of methyl chlorosulfonate to 1-hexene and 1-octene, respectively, is reported.These products were converted by standard techniques into the corresponding sodium and benzylthiuronium β-chlorosulfonic acid salts and sulfonyl chlorides.Dehydrochlorination of these latter products with triethylamine affored regiospecific formation of trans-α,β-unsaturated sulfonyl chlorides, which were transformed by conventional methods into sodium and benzylthiuroniumunsaturated and saturated sulfonic acid salts.Eleven new compositions of matter are reported.