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"Z-S-Pro-S-Val-S-Pro-OtBu" is a peptide sequence consisting of six amino acids: Z (a protecting group), S-Pro (seryl-proline), S-Val (seryl-valine), S-Pro (seryl-proline), and OtBu (a tert-butyl protecting group). This specific arrangement of amino acids is designed to protect certain functional groups during peptide synthesis, which is crucial for maintaining the integrity of the peptide structure. The "Z" and "OtBu" groups are commonly used in peptide chemistry to prevent unwanted side reactions and ensure that the peptide bonds form correctly. The sequence features two S-Pro and S-Val units, which may contribute to the peptide's stability and biological activity. Overall, "Z-S-Pro-S-Val-S-Pro-OtBu" represents a carefully crafted peptide with protective groups that facilitate its synthesis and potential applications in research or therapeutics.

28334-65-8

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28334-65-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 28334-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,3 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 28334-65:
(7*2)+(6*8)+(5*3)+(4*3)+(3*4)+(2*6)+(1*5)=118
118 % 10 = 8
So 28334-65-8 is a valid CAS Registry Number.

28334-65-8Downstream Products

28334-65-8Relevant academic research and scientific papers

STUDIES ON AMINO ACIDS AND PEPTIDES X. HPLC-MEDIATED TEST OF 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE 2,4-DISULFIDE (LAWESSONS'S REAGENT) AS A RACEMIZATIONFREE COUPLING REAGENT IN PEPTIDE SYNTHESIS

Thorsen, M.,Andersen, T. P.,Pedersen, U.,Yde, B.,Lawesson, S.-O.,Hansen. H. F.

, p. 5633 - 5636 (2007/10/02)

The easily available 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide (Lawesson's Reagent), 1, has been tested as a coupling reagent for racemization in peptide synthesis.The assay procedure is separation of stereomeric products by HPLC.Z-S-Pro-S-Val-S-Pro-OtBu and Z-S-Leu-S-Phe-S-Val-OtBu have been used as test peptides in 2+1 segment couplings, and only a small amount of epimerization (0.5 and 0.1percent, respectively) has been observed.

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