283602-68-6Relevant academic research and scientific papers
A radical cyclisation approach to pyroglutamates
Goodall, Karen,Parsons, Andrew F.
, p. 6739 - 6758 (1996)
Treatment of serine-derived N-(α-haloacetamido)dehydroalanine derivatives with tributyltin hydride in boiling benzene or toluene afforded pyroglutamates in 47-84% yield. The radical cyclisation reaction, which proceeded regioselectively in a disfavoured 5
