144001-42-3

Basic information

• Product Name: N-Benzyl-DL-serine Methyl Ester
• Synonyms: N-Benzyl-DL-serine Methyl Ester;Methyl 2-(benzylaMino)-3-hydroxypropanoate;N-(phenylmethyl)Serine methyl ester;N-(Phenylmethyl)-DL-serine methyl ester
• CAS NO: 144001-42-3
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.2417
• Mol File: 144001-42-3.mol

Chemical Properties

• Boiling Point: 351.1±32.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 13.94±0.10(Predicted)
• CAS DataBase Reference: N-Benzyl-DL-serine Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzyl-DL-serine Methyl Ester(144001-42-3)
• EPA Substance Registry System: N-Benzyl-DL-serine Methyl Ester(144001-42-3)

Safety Data

• Hazardous Substances Data: 144001-42-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
N-Benzyl-DL-serine Methyl Ester is used as a reagent in organic synthesis for its ability to contribute to the formation of various chemical compounds. Its unique structure allows it to participate in a range of reactions, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, N-Benzyl-DL-serine Methyl Ester is utilized as a chiral building block. Its chiral nature is valuable in the synthesis of enantiomerically pure compounds, which are essential in the development of drugs with specific biological activities and reduced side effects.
Used in the Production of Biologically Active Molecules:
N-Benzyl-DL-serine Methyl Ester serves as a precursor in the production of biologically active molecules. Its incorporation into these molecules can enhance their pharmacological properties, making it a valuable component in the creation of new therapeutic agents.
Used in the Development of New Materials:
N-Benzyl-DL-serine Methyl Ester is also used in the development of new materials, where its unique structural features can contribute to the properties of the materials being developed. Its versatility in chemical reactions allows for the exploration of its potential in various material science applications.
Used as an Intermediate in Chemical Production:
N-Benzyl-DL-serine Methyl Ester is employed as an intermediate in the production of innovative chemical products. Its role in the synthesis process is crucial for the creation of advanced chemical entities that can be used in various industries, including pharmaceuticals, agrochemicals, and specialty chemicals.

Upstream product

• 2104-89-4 Ser-OMe 
• 100-39-0 benzyl bromide 
• 67-56-1 methanol 
• 106910-76-3 (RS)-N-benzylserine 
• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 100-52-7 benzaldehyde 
• 113729-05-8 3-benzyloxazolidine-4-carboxylate de methyle 
• 2104-89-4 D-serine methyl ester 
• 5874-57-7 R-(-)-serine methyl ester hydrochloride 
• 40216-75-9 (R)-3-Hydroxy-2-{[1-phenyl-meth-(E)-ylidene]-amino}-propionic acid methyl ester 

Downstream Products

• 131110-77-5 (R)-3-benzyl-2,2-dimethyl-4-oxazolidinecarboxylic acid methyl ester 
• 794518-57-3 methyl (2R)-2-(benzylamino)-3-{[tert-butyl(dimethyl)silyl]oxy}propanoate 
• 887128-07-6 methyl (2R)-2-[benzyl(tert-butoxycarbonyl)amino]-3-hydroxypropanoate 
• 852946-10-2 methyl (2R)-3-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-[benzylamino]propanoate 
• 929048-00-0 (7R,9aR)-7-(hydroxymethyl)-8-(phenylmethyl)hexahydropyrazino[2,1-c][1,4]oxazine-6,9-dione 
• 160848-10-2 methyl 2-(N-benzyl-2,2-dichloroethanamido)propenoate 
• 160848-07-7 methyl 2-(N-benzyl-2-chloroethanamido)propenoate 
• 178100-18-0 methyl 2-(N-benzyl-2,2,2-trichloroethanamido)propenoate 
• 283602-70-0 methyl 2-(N-benzyl-2,2-dichloroethanamido)-3-hydroxy propanoate 
• 283602-69-7 methyl 2-(N-benzyldichloroethanamido)-3-(tert-butyldimethylsiloxy)propanoate 
• 283602-71-1 methyl 2-(N-benzyl-2,2-dichloroethanamido)-3-trichloroacetoxypropanoate 
• 160848-04-4 2-[Benzyl-(2-chloro-acetyl)-amino]-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid methyl ester 

Relevant articles and documents

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Deoxyradiofluorination Reaction from β-Hydroxy-α-aminoesters: an Entry to [18F]Fluoroaminoesters under Mild Conditions

We report the conversion of β-hydroxy-α-aminoesters derived from serine, α-methylserine or β-phenylserine to the corresponding [18F]fluorinated α or β-aminoesters by deoxyradiofluorination using [18F]fluoride. The method involved the

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