28419-86-5

Usage

InChI:InChI=1/C8H14O/c1-4-8(6-9)5-7(2)3/h5-7H,4H2,1-3H3

Upstream product

• 123-72-8 butyraldehyde 
• 78-84-2 isobutyraldehyde 
• 187737-37-7 propene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 10349-95-8 2-ethyl-4-methyl-pentanal 
• 56640-31-4 2-ethyl-4-methylpentanoic acid 

Relevant academic research and scientific papers

Directed regio- and stereoselective hydroformylation of mono- and 1,3-disubstituted allylic alcohols: A catalytic approach to the anti-aldol-retron

Regioselective and diastereoselective hydroformylation of mono- and 1,3-disubstituted allylic alcohol o-DPPB esters is described. The products represent synthetically important anti-aldol retrons.

Nitro compounds, process for preparation thereof and use thereof

A new nitro compound of the formula: STR1 wherein R1 and R2 are each lower alkyl or lower alkoxy(lower)alkyl, or STR2 is cyclized to form STR3 X is --O--, --S-- or --NH--, m is an integer 0 or 1, and R3 is carbamoyl, lower alkylcarbamoyl, lower alkanoyl, di-lower alkylaminosulfonyl, lower alkylsulfonyl, oxamoyl or a group of the formula: --(Y)n --R4 wherein Y is --CO--, --SO2 --, --COCH2 -- or STR4 n is an integer of 0 or 1, and R4 is heterocyclic group which is optionally substituted with one or more substituents selected from lower alkyl, lower alkoxy, phenyl, carbamoyl, halogen, amino, lower alkylthio, hydroxy, lower alkylsulfonylamino and carbamoylmethyl, and pharmaceutically acceptable salt thereof, which are useful as vasodilators.

CHEMICAL CONVERSIONS OF BUTYRALDEHYDES DURING SEPARATION OF THE PRODUCTS OF OXO SYNTHESIS.

Preliminary studies of separation of the products of oxo synthesis in presence of cobalt salts revealed substantial (up to 30%) losses of aldehydes, and lowering of the temperature limit of stability of the catalyst to 170-180 degree . In particular, it was found that cobalt salts catalyze aldol condensation. In order to determine the optimal separation conditions, with minimization of losses of aldehydes and alcohols and conservation of catalyst stability, it was necessary to study the principal factors determining the degree and interrelationships of the chemical conversions accompanying separation. It is shown that aldol condensation and formation of acetals occur during isolation of butyraldehydes by continuous fractionation of the products of oxo synthesis. Aldehyde losses due to chemical conversions decrease with increase of temperature in the reboiler, and may be virtually eliminated, while the selectivity of formation of the products of aldol condensation increases.