28482-69-1Relevant academic research and scientific papers
Acetamides and benzamides that are useful in treating sexual dysfunction
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, (2008/06/13)
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
Acetamides and benzamides that are useful in treating sexual dysfunction
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Page 82, (2008/06/13)
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
Acetamides and benzamides that are useful in treating sexual dysfunction
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Page 58, (2010/02/06)
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
The Oxidative Decarboxylation of N-Aroylglycines to N-(Aacetoxymethyl)benzamides and N-Formylbenzamides with Lead(IV) Acetate
Gledhill, Adrian P.,McCall, Carol J.,Threadgill, Michael D.
, p. 3196 - 3201 (2007/10/02)
Treatment of N-aroylglycines that do not bear a strong electron-withdrawing substituents with lead(IV) acetate in acetic acid/acetic anhydride mixtures at 60-100 deg C rapidly gives the corresponding N-(acetoxymethyl)benzamides and N-formylbenzamides in m
1H and 13C NMR Spectra of the Rotational Isomers of N-Hydroxymethylamides and Derivatives
Gate, E. N.,Hooper, D. L.,Stevens, M. F. G.,Threadgill, M. D.,Vaughan, K.
, p. 78 - 82 (2007/10/02)
A series of N-hydroxymethylamides, RCONR'CH2OH, and their O-methyl and O-acetyl derivatives, have been studied by 13C and 1H magnetic resonance spectroscopy.Signals have been assigned to the E- and Z-isomers on the basis of the analysis of the fully coupled spectra, and by comparison of the chemical shifts with those of model compounds.The introduction of the hydroxy, alkoxy or acetoxy groups at the α-position of the N-alkyl moiety causes a significant shift in the equilibrium towards the E-rotamer compared with the unsubstituted N-alkylamide.The predominant effect in determining the E:Z ratio appears to be the steric interaction between the carbonyl oxygen and the α-oxygen in the alkyl moiety; intramolecular hydrogen bonding does not play a significant role in determining the rotamer populations of these molecules.
Clavulanic acid derivatives their preparation and use
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, (2008/06/13)
This invention provides the compounds of the formula (II): STR1 and salts and esters thereof, wherein R1 is H and R3 is H or an aryl, aralkyl, lower alkyl or substituted lower alkyl group or R1 and R3 are joined
