1575-94-6Relevant articles and documents
A simple and one-pot multi-component reaction to the synthesis of methylenebisamides
Mohammadi, Bagher,Khorrami, Bahareh Rezaei
, p. 1089 - 1092 (2018)
Abstract: This work described a simple and efficient method for the synthesis of some methylenebisamide derivatives. The reaction is carried out via a simple multi-component reaction between arylaldehydes, DMSO, and hydroxylamine hydrochloride. Short reaction times, excellent yields of products, inexpensive and readily available starting material, eco-friendly method, easy work-up, and high atom economy are the main advantages of this reaction.
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Gradsten,Pollock
, p. 3079 (1948)
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One-Pot Anodic Conversion of Symmetrical Bisamides of Ethylene Diamine to Unsymmetrical gem-Bisamides of Methylene Diamine
Golub, Tatiana,Dou, Gui-Yuan,Zeng, Cheng-Chu,Becker, James Y.
, p. 7961 - 7964 (2019/10/11)
Symmetrical bisamides of ethylene diamine of type ArCONHCH2CH2NHCOAr undergo anodic C-C bond cleavage in acetonitrile-LiClO4 under controlled-potential electrolysis. The electrogenerated carbocation intermediates react with the solvent acetonitrile to afford unsymmetrical gem-bisamides of type ArCONHCH2NHCOMe in a one-pot reaction. The yields of the latter products are moderate (up to 60%). Other minor products involve two symmetrical gem-bisamides of type ArCONHCH2NHCOAr and MeCONHCH2NHCOMe and fragmentation products (e.g., ArCONHCHO, ArCONH2, and ArCN).
Cobalt(III)-Catalyzed and Dimethyl Sulfoxide-Involved Cross-Coupling of Ketones and Amides for Direct Synthesis of β-Amino Ketones
Xu, Xuefeng,Zhou, Zhi,Wang, Zhipin,Ma, Xinna,Chen, Xin,Zhang, Xu,Yu, Xiyong,Yi, Wei
supporting information, p. 4278 - 4285 (2019/08/12)
A straightforward synthesis of β-amino ketones has been realized by employing ketones and amides as the substrates via cobalt(III)-catalyzed and dimethyl sulfoxide-involved cross-coupling reaction. Experimental investigations revealed that the β-methylsul
