2850-22-8Relevant academic research and scientific papers
Synthesis and biological evaluation of 2-(4-substituted benzene-1-sulfonyl)-N'-(substituted-1-sulfonyl)acetohydrazide as antibacterial agents
Li, Pei,Zhou, Junliang,Liu, Yan,Wang, Xiang
, p. 4559 - 4565 (2020/07/10)
In this study, a series of new sulfone derivatives containing a sulfonohydrazide moiety were synthesized and their structures were determined using 1H NMR, 13C NMR, and HRMS. Then, the in vitro antibacterial activities against Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) were evaluated by performing turbidimeter test. Bioactivity results showed that compound 2-(4-fluorobenzene-1-sulfonyl)-N′-(4-fluorobenzene-1-sulfonyl)acetohydrazide (5g) revealed the best antibacterial activities against Xoo and Xac, with the 50percent effective concentration (EC50) values of 25 and 36?μg/mL, respectively, which were superior to those of thiodiazole copper (110 and 230?μg/mL, respectively) and bismerthiazol (84 and 146?μg/mL, respectively).
Synthesis, characterization and antioxidant activity of bis (arylsulfonylmethyl/arylaminosulfonylmethylazolyl) pyridines
Gunthanakkala, Anil Kumar,Mangali, Madhu Sekhar,Venkatapuram, Padmavathi,Adivireddy, Padmaja
, p. 4164 - 4174 (2020/09/07)
A new class of bis(arylsulfonylmethylazolyl)pyridines and bis(arylaminosulfonylmethyl-azolyl)pyridines were synthesized from the synthetic intermediates methyl arylsulfonylacetic acid hydrazide and methyl arylaminosulfonylacetic acid hydrazide adopting a green methodology-ultrasonication. All the synthesized compounds were resulted in higher yield and in shorter reaction times. The spectral parameters such as IR, 1H NMR, 13C NMR, mass and microanalyzes were used to determine the structures of all the synthesized compounds and were assayed for antioxidant activity. The bis(arylaminosulfonylmethylazolyl)pyridines showed higher radical scavenging activity than the bis(arylsulfonylmethylazolyl)pyridines. Besides, unsubstituted, and methyl substituted compounds exhibited greater activity. Among all the tested compounds 8b and 11b were identified as potential antioxidants.
Synthesis and antimicrobial activity of pyrazolyl 1,3,4-oxadiazoles
Padmavathi, Venkatapuram,Reddy, Gali Sudhakar,Reddy, Guda Dinneswara,Payani, Thalari
scheme or table, p. 482 - 493 (2010/04/06)
The pyrazolyl oxadiazoles are synthesized from arylsulfonylacetic acid methyl ester and benzylsulfonylacetic acid methyl ester. Preliminary antimicrobial screening of the compounds showed that bis heterocycles with a chloro-substituted benzyl moiety exhibited high activity. Copyright Taylor & Francis Group, LLC.
Synthesis of thiadiazoles, triazoles and oxadiazoles from sulfonyl acetic acids via a common route
Padmavathi, Venkatapuram,Thriveni, Pinnu,Reddy, Boggu Jagan Mohan,Padmaja, Adivireddy
, p. 113 - 116 (2007/10/03)
A new class of five membered heterocycles, thiadiazoles, triazoles and oxadiazoles were prepared from sulfonyl acetic acids via acid hydrazides.
