2850-22-8

Basic information

• Product Name: N-AMINO-2-((4-METHYLPHENYL)SULFONYL)ETHANAMIDE
• Synonyms: N-AMINO-2-((4-METHYLPHENYL)SULFONYL)ETHANAMIDE;2-(4-methylbenzenesulfonyl)acetohydrazide
• CAS NO: 2850-22-8
• Molecular Formula: C₉H₁₂N₂O₃S
• Molecular Weight: 228.27
• Mol File: 2850-22-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-AMINO-2-((4-METHYLPHENYL)SULFONYL)ETHANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-AMINO-2-((4-METHYLPHENYL)SULFONYL)ETHANAMIDE(2850-22-8)
• EPA Substance Registry System: N-AMINO-2-((4-METHYLPHENYL)SULFONYL)ETHANAMIDE(2850-22-8)

Safety Data

• Hazardous Substances Data: 2850-22-8(Hazardous Substances Data)

Upstream product

• 3937-96-0 tosylacetic acid 
• 106-45-6 para-thiocresol 
• 14738-27-3 ethyl (p-tolylthio)acetate 
• 50397-64-3 methyl 2-(p-tolylsulfonyl)acetate 
• 2850-19-3 (toluene-4-sulfonyl)-acetic acid ethyl ester 

Downstream Products

• 52287-64-6 N,N'-bis-(toluene-4-sulfonylmethyl)-urea 
• 2850-26-2 (toluene-4-sulfonylmethyl)-carbamic acid ethyl ester 
• 1246440-75-4 2-(p-methylphenylaminosulfonylmethyl)-5-(p-methylphenylsulfonylmethyl)-1,3,4-oxadiazole 

Relevant articles and documents

Synthesis and biological evaluation of 2-(4-substituted benzene-1-sulfonyl)-N'-(substituted-1-sulfonyl)acetohydrazide as antibacterial agents

In this study, a series of new sulfone derivatives containing a sulfonohydrazide moiety were synthesized and their structures were determined using 1H NMR, 13C NMR, and HRMS. Then, the in vitro antibacterial activities against Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) were evaluated by performing turbidimeter test. Bioactivity results showed that compound 2-(4-fluorobenzene-1-sulfonyl)-N′-(4-fluorobenzene-1-sulfonyl)acetohydrazide (5g) revealed the best antibacterial activities against Xoo and Xac, with the 50percent effective concentration (EC50) values of 25 and 36?μg/mL, respectively, which were superior to those of thiodiazole copper (110 and 230?μg/mL, respectively) and bismerthiazol (84 and 146?μg/mL, respectively).

Synthesis and antimicrobial activity of pyrazolyl 1,3,4-oxadiazoles

The pyrazolyl oxadiazoles are synthesized from arylsulfonylacetic acid methyl ester and benzylsulfonylacetic acid methyl ester. Preliminary antimicrobial screening of the compounds showed that bis heterocycles with a chloro-substituted benzyl moiety exhibited high activity. Copyright Taylor & Francis Group, LLC.