2850-19-3

Basic information

• Product Name: ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE
• Synonyms: BUTTPARK 52\04-49;ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE;Acetic acid, (p-tolylsulfonyl)-, ethyl ester;Ethyl [(4-methylphenyl)sulfonyl]acetate;Ethyl 2-(para-tolylsulfonyl)-acetate;Ethyl alpha-(p-toluenesulfonyl)acetate;Ethyl alpha-(p-tolylsulfonyl)acetate;ethyl (4-tolylsulphonyl)acetate
• CAS NO: 2850-19-3
• Molecular Formula: C₁₁H₁₄O₄S
• Molecular Weight: 242.29
• EINECS: 220-656-3
• Mol File: 2850-19-3.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 394°C at 760 mmHg
• Flash Point: 192.1°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 2.05E-06mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE(2850-19-3)
• EPA Substance Registry System: ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE(2850-19-3)

Safety Data

• Hazardous Substances Data: 2850-19-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O4S/c1-3-15-11(12)8-16(13,14)10-6-4-9(2)5-7-10/h4-7H,3,8H2,1-2H3

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 105-36-2 ethyl bromoacetate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 623-73-4 diazoacetic acid ethyl ester 
• 106-45-6 para-thiocresol 
• 98-59-9 p-toluenesulfonyl chloride 
• 64-17-5 ethanol 
• 3937-96-0 tosylacetic acid 
• 5720-05-8 4-methylphenylboronic acid 
• 104690-31-5 ethyl 2-iodo-3-oxobutanoate 
• 141-97-9 ethyl acetoacetate 
• 152797-10-9 2-Bromo-3-methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1H-pyrrole 
• 996-82-7 sodium diethylmalonate 

Downstream Products

• 125786-14-3 2-(Toluene-4-sulfonyl)-hexanoic acid ethyl ester 
• 74016-10-7 (E)-5,9-Dimethyl-2-(toluene-4-sulfonyl)-deca-4,8-dienoic acid ethyl ester 
• 1186668-69-8 C₂₃H₂₉NO₆S 
• 33629-77-5 3,4-bis(4-methylbenzene-1-sulfonyl)furoxan 
• 1313429-18-3 3-(3-methoxy-phenyl)-2-(toluene-4-sulfonyl)-pentanoic acid ethyl ester 
• 1313429-22-9 3-(3-methoxy-phenyl)-2-methyl-2-(toluene-4-sulfonyl)-pentanoic acid ethyl ester 
• 21968-56-9 p-Tolyl-<2-aethoxycarbonyl-benzyl>-sulfon 

Relevant articles and documents

Modulation of photochemical oxidation of thioethers to sulfoxides or sulfones using an aromatic ketone as the photocatalyst

We have developed an eco-friendly and chemo-selective photocatalytic synthesis of sulfoxides or sulfones via oxidation of sulfides (thioethers) at ambient temperature using air or O2 as the oxidant. An inexpensive thioxanthone was used as the photocatalyst. Our method offers excellent chemical yields and good functional group tolerance. The hydrogen bonding between hexafluoro-2-propanol (HFIP) and sulfoxides may play an important role in minimizing the over-oxidization of sulfoxides.

Modular Synthesis of Carbon-Substituted Furoxans via Radical Addition Pathway. Useful Tool for Transformation of Aliphatic Carboxylic Acids Based on "build-and-Scrap" Strategy

Utilizing radical chemistry, a new general C-C bond formation on the furoxan ring was developed. By taking advantage of the lability of furoxans, a wide variety of transformation of the synthesized furoxans have been demonstrated. Thus, this developed methodology enabled not only the modular synthesis of furoxans but also short-step transformations of carboxylic acids to a broad range of functional groups.

Method for preparing beta-carbonyl sulfone

The invention discloses a method for preparing beta-carbonyl sulfone. The preparation method comprises the following steps: by taking an alpha-carbonyl diazo compound and sodium arylsulfinate as reaction substrates, cheap silver nitrate as an optimal catalyst, 1, 10-phenanthroline as a ligand and potassium persulfate as an oxidant, carrying out coupling reaction in a mixed solvent of acetonitrileand water to obtain the beta-carbonyl sulfone compound. Compared with the prior art, the method has the advantages of wide reaction substrate range, short reaction time, high reaction yield, mild reaction conditions and the like. Non-toxic and harmless reagents are used as reaction raw materials, so that the method is harmless to the environment and meets the requirements of modern green chemicaldevelopment. Post-reaction treatment is simple, and separation and purification are facilitated. In addition, the reaction can realize gram-scale synthesis, and lays a foundation for practical application.