2850-40-0

Usage

Category

Natural stimulant

Presence

Found in coffee, tea, and many other beverages

Function

Stimulates the central nervous system

Effects

Increases alertness, reduces fatigue, improves mental alertness, enhances physical performance, and reduces headaches

Safety

Moderate consumption is generally considered safe

Side Effects

Anxiety, insomnia, and increased heart rate (with excessive intake)

InChI:InChI=1/C10H14N4O2/c1-5(2)7-11-6-8(12-7)13(3)10(16)14(4)9(6)15/h5H,1-4H3,(H,11,12)

Upstream product

• 58-55-9 theophylline 
• 78-84-2 isobutyraldehyde 
• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 79-31-2 isobutyric Acid 

Relevant academic research and scientific papers

Dioxygen-Mediated Decarbonylative C-H Alkylation of Heteroaromatic Bases with Aldehydes

An operationally simple and economical method for the direct alkylation of heteroaromatic bases employing readily available aldehydes as alkyl radical precursors and molecular oxygen as a reagent is presented. This simple transformation demonstrates a broad substrate scope with respect to aldehydes and nitrogen heterocycles, enabling the introduction of several medicinally important yet challenging alkyl moieties, such as ethyl, isopropyl, tert-butyl, and cyclohexyl to the different classes of heterocyclic bases in good to excellent yields. A simple method for the direct alkylation of heteroaromatic bases with aldehydes as inexpensive alkyl radical precursors and molecular oxygen as a reagent is presented. This transformation demonstrates a broad substrate scope with respect to aldehydes and nitrogen heterocycles, enabling the introduction of various alkyl moieties to heterocyclic bases (>40 examples) in good to excellent yields.