28504-41-8

Upstream product

• 67-56-1 methanol 
• 170997-34-9 1,1'-(1,10-decanediyl)-bis<4-nitro-2-(trichloroacetyl)-1H-pyrrole> 
• 170997-33-8 1,1'-(1,10-decanediyl)-bis<2-(trichloroacetyl)-1H-pyrrole> 
• 62515-92-8 N-p-methoxyphenyl-2,4,6-cycloheptatriene-1-imine 
• 100-63-0 phenylhydrazine 
• 539-80-0 Tropone 

Downstream Products

• 141493-67-6 1-anilino-3-chloro-1-azaazulen-2(1H)-one 
• 141493-64-3 1-anilino-1-azaazulen-2(1H)-one 
• 141493-70-1 1-anilino-3-phenyl-1-azaazulen-2(1H)-one 
• 106361-50-6 3-phenyl-1-(phenylamino)-3,3a-dihydrocyclohepta[b]pyrrol-2(1H)-one 

Relevant academic research and scientific papers

DESIGN AND SYNTHESIS OF SEQUENCE-SPECIFIC DNA MINOR GROOVE RECOGNIZING LIGANDS OF THE CROSS-LINKED LEXITROPSIN CLASS

On the basis of previous studies on pyrrole-containing cross-linked lexitropsins, symmetric and non-symmetric cross-linked lexitropsins incorporating imidazole rings are designed to bind selectively to GC-containing oligonucleotide sequences and their syntheses are described.

FORMATIONS OF 1,1'-BIAZAAZULANONES THROUGH, -TYPE CYCLOADDITION REACTIONS OF TROPONE AZINE WITH HETEROCUMULENES

Reaction of N-aryl-2,4,6-cycloheptatrien-1-imine with hydrazine afforded tropone azine, which reacted with chloroketenes to give 1,1'-biazaazulanones via -type cycloadducts followed by elimination of hydrochloride.The similar reaction using phenyl isocyanate afforded a -type 1:2 cycloadduct, while the reaction with phenyl isocyanate yielded only a 1:1 cycloadduct. 15N and 13C nmr spectra on C=N bond of tropone azine showed a minor contribution of a dipolar structure compared with the case of N-aryl-2,4,6-cycloheptatrien-1-imines.

Reaction of Tropone Hydrazones with Heterocumulenes such as Isocyanate, Ketene, and Sulfene

Tropone benzoyl- and tosylhydrazones underwent the cycloaddition reaction with isocyanates to afford the cycloheptaimidazolin-2-one derivatives.This means that these hydrazones behaved as 8-amino-8-azaheptafulvenes.Also, the tropone hydrazones re