28523-15-1

Basic information

• Product Name: 2-(4-chlorophenyl)-2-phenylacetaldehyde
• Synonyms: 2-(4-chlorophenyl)-2-phenylacetaldehyde
• CAS NO: 28523-15-1
• Molecular Weight: 230.694
• Mol File: 28523-15-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-2-phenylacetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-2-phenylacetaldehyde(28523-15-1)
• EPA Substance Registry System: 2-(4-chlorophenyl)-2-phenylacetaldehyde(28523-15-1)

Safety Data

• Hazardous Substances Data: 28523-15-1(Hazardous Substances Data)

Upstream product

• 6425-12-3 1-phenyl-2,2-dimorpholin-1-yl-ethanone 
• 72721-75-6 Bis(1,1-acetylamino)-2-hydroxy-2-phenylaethan 
• 53780-26-0 2-(4-chlorophenyl)-2-phenyloxirane 
• 18218-20-7 1-(4-chlorophenyl)-1-phenylethene 
• 72721-58-5 2-acetylamino-2-morpholin-4-yl-1-phenyl-ethanone 
• 28291-10-3 trans-2-(4-chlorobenzenyl)-3-phenyl-oxirane 
• 105-39-5 chloroacetic acid ethyl ester 
• 134-85-0 4-chlorobenzophenone 
• 32569-84-9 ethoxyethynylbenzene 
• 40891-23-4 N,N'-(benzoylmethylene)diacetamide 
• 72721-81-4 N-[1-Acetylamino-2-(4-chloro-phenyl)-2-phenyl-ethyl]-acetamide 
• 28291-10-3 2-(4-chlorophenyl)-3-phenyloxirane 

Downstream Products

• 21771-88-0 α-(4-chlorophenyl)phenylacetic acid 
• 1042964-72-6 3-(4-chlorophenyl)-3-phenylprop-1-ene-1,1-dicarbonitrile 
• 53779-99-0 3-Dimethylamino-1-p-chlorophenyl-1-phenyl-propan-2-ol 
• 129315-83-9 trans-(1S^*,2R^*)-2-(4-chlorophenyl)-2-phenylcyclopentanol 
• 129315-83-9 cis-(1R^*,2R^*)-2-(4-chlorophenyl)-2-phenylcyclopentanol 
• 129315-76-0 2-(4-chlorophenyl)-2-phenylcyclopentanone 
• 129315-96-4 2-(4-chlorophenyl)-2-phenyl-4-pentenoic acid 
• 129315-93-1 2-(4-chlorophenyl)-2-phenylcyclopent-4-enone 

Relevant articles and documents

Mild Iridium-Catalysed Isomerization of Epoxides. Computational Insights and Application to the Synthesis of β-Alkyl Amines

The isomerization of epoxides to aldehydes using the readily available Crabtree's reagent is described. The aldehydes were transformed into synthetically useful amines by a one-pot reductive amination using pyrrolidine as imine-formation catalyst. The reactions worked with low catalyst loadings in very mild conditions. The procedure is operationally simple and tolerates a wide range of functional groups. A DFT study of its mechanism is presented showing that the isomerization takes place via an iridium hydride mechanism with a low energy barrier, in agreement with the mild reaction conditions. (Figure presented.).

An electric field-induced change in the selectivity of a metal oxide-catalyzed epoxide rearrangement

The rearrangement of cis-stilbene oxide catalyzed by Al2O 3 was studied in the presence of interfacial electric fields. Thin films of Al2O3 deposited on Si electrodes were used as the opposing walls of a reaction vessel. Application of a voltage across the electrodes engendered electrochemical double layer formation at the Al 2O3-solution interface. The aldehyde to ketone product ratio of the rearrangement was increased by up to a factor of 63 as the magnitude of the double layer charge density was increased. The results support a field-dipole effect on the selectivity of the catalytic reaction.

Diastereoselectivity in the reduction of sterically unbiased 2,2-diarylcyclopentanones

Reduction of sterically unbiased 2-phenyl-2-(4-X-phenyl)cyclopentanones 1 (X = NO2, Br, Cl, OCH3, OH, NH2) with either sodium borohydride in methanol or lithium borohydride in tetrahydrofuran at 0°C produced diastereomeric