18218-20-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(1-(4-chlorophenyl)vinyl)benzene is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(1-(4-chlorophenyl)vinyl)benzene serves as a building block for the creation of novel agrochemicals, contributing to the development of more effective and environmentally friendly products.
Used in Fine Chemicals Production:
1-(1-(4-chlorophenyl)vinyl)benzene is utilized as an essential component in the production of fine chemicals, which are high-purity chemicals used in various applications, such as research, diagnostics, and specialty manufacturing.
Used in Fragrance Industry:
As a fragrance ingredient, 1-(1-(4-chlorophenyl)vinyl)benzene is employed in the formulation of perfumes and other scented products, adding unique and desirable aromas to these products.
Used in Specialty Polymers Production:
In the polymer industry, 1-(1-(4-chlorophenyl)vinyl)benzene is used in the synthesis of specialty polymers, which possess unique properties and are used in various high-performance applications, such as coatings, adhesives, and advanced materials.

Upstream product

• 99-91-2 para-chloroacetophenone 
• 917-64-6 methyl magnesium iodide 
• 134-85-0 4-chlorobenzophenone 
• 100-42-5 styrene 
• 106-39-8 bromochlorobenzene 
• 460742-55-6 4-nitro-benzoic acid 1-(4-chloro-phenyl)-1-phenyl-ethyl ester 
• 1073-67-2 4-vinylbenzyl chloride 
• 108-86-1 bromobenzene 
• 108-90-7 chlorobenzene 
• 20618-65-9 4-Chloro-benzoic acid isopropenyl ester 
• 2206-94-2 1-acetoxy-1-phenylethene 
• 7519-91-7 tris(4-chlorophenyl)boroxine 
• 29540-84-9 4-chlorophenyl trifluoromethanesulfonate 
• 106-48-9 4-chloro-phenol 

Downstream Products

• 17684-15-0 (Z)-3-(4-chlorophenyl)-3-phenylacrylic acid 
• 17684-15-0 (E)-3-(4-chlorophenyl)-3-phenylacrylic acid 
• 99632-23-2 (Z)-1-phenyl-1-(p-chlorophenyl)-2-bromoethylene 
• 99632-31-2 (E)-1-(2-bromo-1-phenylvinyl)-4-chlorobenzene 
• 109610-59-5 3,8-Bis-phenyl-3,8-bis(p-chlorophenyl)-2,7-dioxaspiro<4,4>nonane-1,6-dione 
• 62051-44-9 5-(4-Chloro-phenyl)-benzo[a]anthracene-7,12-dione 
• 62051-40-5 2-Chloro-5-phenyl-benzo[a]anthracene-7,12-dione 
• 74925-08-9 1-Chloro-4-(2,2-difluoro-2-phenyl-ethyl)-benzene 
• 74925-07-8 1-Chloro-4-(1,1-difluoro-2-phenyl-ethyl)-benzene 
• 58617-64-4 1-fluoro-2-iodo-1-phenyl-1-(4'-chlorophenyl)ethane 
• 106403-92-3 1-Chloro-4-(1,2-dibromo-1-phenyl-ethyl)-benzene 
• 134-85-0 4-chlorobenzophenone 
• 144889-04-3 1-Chloro-4-(2,2-dinitro-1-phenyl-vinyl)-benzene 
• 116437-71-9 1-Chloro-4-((Z)-2-nitro-1-phenyl-vinyl)-benzene 

Relevant academic research and scientific papers

Electrochemical fluorosulfonylation of alkenes to access vicinal fluorinated sulfones derivatives

Herein, we report a practical and efficient fluorosulfonylation of the various alkenes with sulfonyl radical sources (RSO2NHNH2) and Et3N·3HF as cost-effective fluorination reagents under mild conditions. Remarkably, this

Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes

Photoinduced hydroarylation of alkenes is an appealing synthetic strategy for arene functionalization. Herein, we demonstrated that aryl radicals generated from electron-deficient aryl chlorides/bromides could be trapped by an array of terminal/internal aryl alkenes in the presence of [Pt(O^N^C^N)] under visible-light (410 nm) irradiation, affording anti-Markovnikov hydroarylated compounds in up to 95 % yield. Besides, a protocol for [Pt(O^N^C^N)]-catalyzed intramolecular photocyclization of acrylanilides to give structurally diverse 3,4-dihydroquinolinones has been developed.

TMSOTf-mediated synthesis of skipped dienes through the addition of olefins to imines and semicyclicN,O-acetals

A novel approach to skipped dienes has been developed through the TMSOTf-mediated one-pot addition-substitution of olefins2a,2fand2gwith imines1a-1g, and a series of aryl substituted skipped dienes3aa-3gfwere accordingly obtained in 62%-94% yields. Moreov

Electrochemistry enabled selective vicinal fluorosulfenylation and fluorosulfoxidation of alkenes

Both sulfur and fluorine play important roles in organic synthesis, the life science, and materials science. The direct incorporation of these elements into organic scaffolds with precise control of the oxidation states of sulfur moieties is of great significance. Herein, we report the highly selective electrochemical vicinal fluorosulfenylation and fluorosulfoxidation reactions of alkenes, which were enabled by the unique ability of electrochemistry to dial in the potentials on demand. Preliminary mechanistic investigations revealed that the fluorosulfenylation reaction proceeded through a radical-polar crossover mechanism involving a key episulfonium ion intermediate. Subsequent electrochemical oxidation of fluorosulfides to fluorosulfoxides were readily achieved under a higher applied potential with the adventitious H2O in the reaction mixture.

Direct 1,2-Dicarbonylation of Alkenes towards 1,4-Diketones via Photocatalysis

1,4-Dicarbonyl compounds are intriguing motifs and versatile precursors in numerous pharmaceutical molecules and bioactive natural compounds. Direct incorporation of two carbonyl groups into a double bond at both ends is straightforward, but also challenging. Represented herein is the first example of 1,2-dicarbonylation of alkenes by photocatalysis. Key to success is that N(n-Bu)4+ not only associates with the alkyl anion to avoid protonation, but also activates the α-keto acid to undergo electrophilic addition. The α-keto acid is employed both for acyl generation and electrophilic addition. By tuning the reductive and electrophilic ability of the acyl precursor, unsymmetric 1,4-dicarbonylation is achieved for the first time. This metal-free, redox-neutral and regioselective 1,2-dicarbonylation of alkenes is executed by a photocatalyst for versatile substrates under extremely mild conditions and shows great potential in biomolecular and drug molecular derivatization.

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

Deaminative carbonylative coupling of alkylamines with styrenes under transition-metal-free conditions

A transition-metal-free deaminative carbonylation of alkylamines with styrenes has been developed. The reaction shows good functional group compatibility and various α,β-unsaturated ketones were obtained in moderate to good yields. The alkyl radical generated from Katritzky salts via base-promoted C-N bond cleavage is one of the key intermediates in this reaction. This journal is

Bimolecular vinylation of arenes by vinyl cations

Styrene derivatives can be easily synthesized from vinyl triflates and arenes under mild reaction conditions, using [Li][Al(OC(CF3)3)4] as a catalyst and LiHMDS as a base. This transformation is likely to involve a vinyl cation intermediate as an electrophile, which is corroborated by DFT calculations, deuterium-labeling and other control experiments. The use of an inert weakly coordinating anion is a decisive factor in this bimolecular vinylation process. This journal is

DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS

The present invention relates to indane derivatives of the formula (I) and mixtures thereof, wherein X is selected from groups of the formulae -A-NH2 or -A-(NAr2), wherein A is a chemical bond or phenylene which is unsubstituted or substituted

Bromomethyl Silicate: A Robust Methylene Transfer Reagent for Radical-Polar Crossover Cyclopropanation of Alkenes

A general protocol for visible-light-induced cyclopropanation of alkenes was developed with bromomethyl silicate as a methylene transfer reagent, offering a robust tool for accessing highly valuable cyclopropanes. In addition to α-aryl or methyl-substituted Michael acceptors and styrene derivatives, the unactivated 1,1-dialkyl ethylenes were also shown to be viable substrates. Apart from realizing the cyclopropanation of terminal alkenes, the methyl transfer reaction has been further demonstrated to be amenable to the internal olefins. The photocatalytic cyclopropanation of 1,3-bis(1-arylethenyl)benzenes was also achieved, giving polycyclopropane derivatives in excellent yields. With late-stage cyclopropanation as the key strategy, the synthetic utility of this transformation was also demonstrated by the total synthesis of LG100268.