28547-23-1

Basic information

• Product Name: 4-BENZOYLOXYBENZOIC ACID
• Synonyms: 4-BENZOYLOXYBENZOIC ACID;Para-Benzoyloxybenzoic Acid
• CAS NO: 28547-23-1
• Molecular Formula: C₁₄H₁₀O₄
• Molecular Weight: 242.23
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 28547-23-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 424.1°Cat760mmHg
• Flash Point: 164.2°C
• Appearance: /
• Density: 1.306g/cm³
• Vapor Pressure: 5.97E-08mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 4-BENZOYLOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZOYLOXYBENZOIC ACID(28547-23-1)
• EPA Substance Registry System: 4-BENZOYLOXYBENZOIC ACID(28547-23-1)

Safety Data

• Hazardous Substances Data: 28547-23-1(Hazardous Substances Data)

Usage

Uses

Para-Benzoyloxybenzoic Acid, is an intermediate in the synthesis of pyridazinone derivatives, acting as platelet aggregation inhibitors.

InChI:InChI=1/C14H10O4/c15-13(16)10-6-8-12(9-7-10)18-14(17)11-4-2-1-3-5-11/h1-9H,(H,15,16)

Upstream product

• 106737-30-8 4-(1-hydroxy-1-phenylethyl)benzoic acid 
• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 87770-86-3 p-(hydroxymethyl)phenyl benzoate 
• 614-34-6 p-cresyl benzoate 
• 75915-29-6 4-benzoyloxybenzoic acid methyl ester 
• 98-88-4 benzoyl chloride 
• 86960-46-5 4-n-decanoyloxybenzoic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 121-90-4 m-nitrobenzoic acid chloride 
• 861306-34-5 4-ethoxycarbonyloxy-3-nitro-benzoic acid 
• 861377-45-9 4-ethoxycarbonyloxy-3-nitro-benzoyl chloride 
• 582-61-6 benzoyl azide 
• 89882-93-9 4-(3-nitro-benzoyloxy)-benzoic acid 
• 151-50-8 potassium cyanide 

Downstream Products

• 58860-84-7 4-(benzoyloxy)benzoyl chloride 
• 93-99-2 benzoic acid phenyl ester 
• 2714-93-4 4-fluorophenyl benzoate 
• 1621377-79-4 1,3-bis(4-(benzoyloxy)phenyl)-1,2-dihydrobenzo[1,2,4]triazin-2-yl 
• 1621378-03-7 4-benzoyloxy-N-phenylbenzimidoyl chloride 
• 1621377-96-5 4-benzoyloxy-N-(4-(trifluoromethyl)phenyl)benzimidoyl chloride 
• 300726-73-2 4-benzoyloxybenzanilide 
• 1621377-93-2 4-benzoyloxy-N-(4-(trifluoromethyl)phenyl)benzamide 
• 1621377-91-0 N'-(4-(benzoyloxy)phenyl)-N-phenyl-4-(benzoyloxy)benzenecarbohydrazonamide 
• 1621377-83-0 N'-(4-(benzoyloxy)phenyl)-N-[4-(trifluoromethyl)phenyl]-4-(benzoyloxy)benzenecarbohydrazonamide 
• 1621378-13-9 C₂₀H₁₃F₃N₃O₂ 
• 1621377-69-2 7-(trifluoromethyl)-1-(4-(benzoyloxy)phenyl)-3-(4-(benzyloxy)phenyl)-1,2-dihydrobenzo[1,2,4]triazin-2-yl 
• 85800-06-2 Phenyl-4(4-benzoyloxy)benzoyloxybenzoate 
• 75915-29-6 4-benzoyloxybenzoic acid methyl ester 

Relevant articles and documents

Photo-induced deep aerobic oxidation of alkyl aromatics

Oxidation is a major chemical process to produce oxygenated chemicals in both nature and the chemical industry. Presently, the industrial manufacture of benzoic acids and benzene polycarboxylic acids (BPCAs) is mainly based on the deep oxidation of polyalkyl benzene, which is somewhat suffering from environmental and economical disadvantage due to the formation of ozone-depleting MeBr and corrosion hazards of production equipment. In this report, photo-induced deep aerobic oxidation of (poly)alkyl benzene to benzene (poly)carboxylic acids was developed. CeCl3 was proved to be an efficient HAT (hydrogen atom transfer) catalyst in the presence of alcohol as both hydrogen and electron shuttle. Dioxygen (O2) was found as a sole terminal oxidant. In most cases, pure products were easily isolated by simple filtration, implying large-scale implementation advantages. The reaction provides an ideal protocol to produce valuable fine chemicals from naturally abundant petroleum feedstocks. [Figure not available: see fulltext.].

Effects of neutral and charged substituents on the infrared carbonyl stretching frequencies in phenyl and alkyl benzoates in DMSO

The carbonyl infrared stretching frequencies for 57 meta-, para- and ortho-substituted phenyl benzoates, C6H5CO2C6H4-X and alkylbenzoates, C6H5CO2R, containing besides neutral substituents the charged substituents in phenoxy and alkoxy part in dimethyl sulfoxide (DMSO) have been recorded. The carbonyl stretching frequencies, νCO, for meta- and para-substituted phenyl esters of benzoic acids in the case of neutral substituents were found to correlate well with the substituent constants, σ°. The νCO values for ortho derivatives correlated with the inductive substituent constants, σI, only. The values of constants for charged substituents, σ°±, calculated on the basis of the νCO and the 13C NMR chemical shifts, δCO, in DMSO agree well with the σ°± values for the corresponding ion pairs reported by Hoefnagel and Wepster and those determined from the log k values of the alkaline hydrolysis in 4.4 M NaCl solution at 50 °C. Thus, the values of substituent constants for ion pairs of charged substituents estimated on the basis of aqueous data could be successfully used in non-aqueous solution (DMSO) simultaneously with neutral substituents in case the charged substituents were not completely ionized and are in ion pair form. Copyright

Method For Producing Acyloxy Benzoic Acids

The invention relates to a method for producing acyloxy benzoic acids of the formula (I), in which R1 is a linear or branched saturated alkyl group with 6 to 30 carbon atoms, a linear or branched mono- or polyunsaturated alkenyl group with 6 to 30 carbon atoms, or an aryl group with 6 to 30 carbon atoms. The acyloxy benzoic acids of the formula (I) are produced from para-hydroxy benzoic acid and a corresponding carboxylic acid halogenide in the presence of a base and are advantageously suitable for use as activators for hydrogen peroxide.