28583-69-9

Upstream product

• 37439-80-8 1-acetoxy-3-acetylamino-2-allyl-benzene 
• 37439-82-0 2-acetoxy-4-acetylamino-1-allyl-benzene 
• 37439-78-4 N-(3-(allyloxy)phenyl)acetamide 
• 121-69-7 N,N-dimethyl-aniline 
• 621-42-1 meta-hydroxyacetanilide 

Downstream Products

• 102878-27-3 2-Allyl-5-amino-phenol 
• 111063-68-4 acetic acid-[4-allyl-3-(2-diethylamino-ethoxy)-anilide] 
• 340774-74-5 acetic acid-(2-allyl-3-methoxy-anilide) 
• 875876-18-9 acetic acid-(4-allyl-3-methoxy-anilide) 
• 55304-05-7 4-acetylamino-2-methoxy-benzoic acid 
• 873990-87-5 4-allyl-3-methoxy-aniline 
• 28583-68-8 2-[(4-Allyl-3-cyclopropylmethoxy-phenylamino)-methylene]-malonic acid diethyl ester 
• 28583-67-7 4-Allyl-3-cyclopropylmethoxy-phenylamine 
• 28771-96-2 N-(4-Allyl-3-cyclopropylmethoxy-phenyl)-acetamide 

Relevant academic research and scientific papers

1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE

The present invention provides a compound represented by the formula (1) or a pharmacologically acceptable salt thereof, or a hydrate thereof (provided that a compound in which all of R4a, R4b, and R4c are hydrogen atoms is excluded.): [wherein R1 represents a hydrogen atom, R2 represents a hydrogen atom, R3 represents the formula: wherein R4a, R4b, and R4c are the same as or different from each other and each represents a hydrogen atom, a C1-6 alkyl group or a C1-6 alkoxy group, etc.]

Synthesis of 7-methoxybenzolactam-V8 using a diastereoselective Strecker synthesis

7-Methoxybenzolactam-V8 (4) was synthesized using a diastereoselective Strecker reaction as the key step employing an ortho-substituted phenylacetaldehyde and (R)-phenylglycinol as the chiral auxiliary.