55304-05-7

Basic information

• Product Name: Benzoic acid, 4-(acetylamino)-2-methoxy-
• CAS NO: 55304-05-7
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Mol File: 55304-05-7.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(acetylamino)-2-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(acetylamino)-2-methoxy-(55304-05-7)
• EPA Substance Registry System: Benzoic acid, 4-(acetylamino)-2-methoxy-(55304-05-7)

Safety Data

• Hazardous Substances Data: 55304-05-7(Hazardous Substances Data)

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 50-86-2 4-acetamidosalicylic acid 
• 121-69-7 N,N-dimethyl-aniline 
• 37439-78-4 N-(3-(allyloxy)phenyl)acetamide 
• 37439-82-0 2-acetoxy-4-acetylamino-1-allyl-benzene 
• 28583-69-9 acetic acid-(4-allyl-3-hydroxy-anilide) 
• 4093-29-2 methyl 4-(acetylamino)-o-anisate 
• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 
• 2486-80-8 4-amino-2-methoxybenzoic acid 
• 108-24-7 acetic anhydride 
• 1134-65-2 2-methoxy-4-acetyl-amino-benzaldehyde 
• 875876-18-9 acetic acid-(4-allyl-3-methoxy-anilide) 

Downstream Products

• 112885-48-0 4-Acetylamino-N-(4-benzyl-morpholin-2-ylmethyl)-2-methoxy-benzamide 
• 1304076-77-4 4-chlorobenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-74-1 benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-70-7 4-acetamido-2-methoxybenzoyl hydrazine 
• 1304076-92-3 C₂₀H₂₁N₃O₅S 
• 908085-25-6 C₂₀H₂₁N₃O₆S 
• 1304076-88-7 C₁₉H₁₉N₃O₅S 
• 1304076-87-6 C₁₉H₁₉N₃O₅S 
• 908085-10-9 C₁₉H₁₈ClN₃O₄S 
• 1304076-86-5 C₁₉H₁₉N₃O₄S 
• 1304076-83-2 4-methoxy-benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 908089-55-4 4-hydroxy-3-methoxy-benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-80-9 4-hydroxybenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 
• 1304076-79-6 2-hydroxybenzal-(4'-acetamido-2'-methoxybenzoyl)hydrazine 

Relevant articles and documents

Aminobenzoic acid derivative and preparation method and application thereof

The invention relates to an aminobenzoic acid derivative and a preparation method and application thereof, and belongs to the field of medicinal chemistry, and the structural formula of the aminobenzoic acid derivative is shown in the specification, R is alkyl, substituted phenyl, heteroaromatic ring group or substituted styryl; R is alkyl; R is alkyl, substituted phenyl or benzyl; R is alkyl; R is guanidyl; and R is alkyl. The preparation method is simple and high in yield. Most compounds of the invention have good influenza virus neuraminidase inhibition activity.

Synthesis and evaluation of novel radioiodinated benzamides for malignant melanoma

The imaging potential of a series of [123I]benzamides was studied in mice bearing B16F0 melanoma tumors. Compound [123I]25 exhibited tumor uptake >8 %ID/g at 1 h, while that of [123I]14d and [123I]25 reached a maximum of 9-12 %ID/g at 6 h. Standardized uptake values of [123I]14d were higher than 100 between 24 and 72 h after injection. In haloperidol treated animals, the tumor uptake of [ 123I]14d was not significantly different to controls, while significant reduction of [123I]25 uptake was observed, supporting that [123I]14d uptake relates to melanin interaction, whereas part of the mechanism of [123I]25 uptake is related to its σ1-receptor affinity. Benzamides 14d and 25, which display rapid and high tumor uptake, appear to be promising imaging agents for melanoma detection, while 14d, which displays a long lasting and high melanoma/nontarget ratio, is more suitable for evaluation as a potential radiotherapeutic.