28627-00-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Chlorotetrafluoropropionyl fluoride is used as a key intermediate in the synthesis of various pharmaceuticals. Its reactivity allows for the creation of new compounds with potential medicinal properties, contributing to the development of novel drugs.
Used in Agrochemical Industry:
In the agrochemical sector, CTFPOF serves as an essential component in the production of pesticides and other crop protection agents. Its incorporation into these products enhances their effectiveness and contributes to improved agricultural yields.
Used in Fine Chemicals Production:
2-Chlorotetrafluoropropionyl fluoride is utilized as an intermediate in the manufacturing process of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, dyes, and flavorings.
Used in Fluorinated Polymers and Surfactants:
CTFPOF plays a crucial role in the production of fluorinated polymers and surfactants, which are known for their unique properties such as non-stick surfaces, water and oil repellency, and thermal stability. These materials are widely used in various industries, including textiles, coatings, and cleaning products.
Used in Organic Synthesis as a Reagent:
As a reagent in organic synthesis, 2-Chlorotetrafluoropropionyl fluoride is employed in the fluorination of organic compounds. This process allows for the introduction of fluorine atoms into organic molecules, which can significantly alter their chemical and physical properties, leading to the development of new materials and compounds with specific applications.
Due to the highly reactive and toxic nature of 2-Chlorotetrafluoropropionyl fluoride, it is imperative to handle 2-CHLOROTETRAFLUOROPROPANOYL FLUORIDE with extreme caution and implement proper safety measures during its use in various applications.

InChI:InChI=1/C3ClF5O/c4-2(6,1(5)10)3(7,8)9

Upstream product

• 41255-94-1 2-chlorohexafluoropropyl fluorosulfate 
• 6066-46-2 2-chlorotetrafluoropropionyl chloride 
• 428-59-1 Hexafluoropropene oxide 
• 422-61-7 perfluoropropanoyl fluoride 

Downstream Products

• 353-50-4 Carbonyl fluoride 
• 374-07-2 1,1-dichlorotetrafluoroethane 
• 152239-95-7 C₃Cl₂F₆O 
• 76-15-3 Chloropentafluoroethane 

Relevant academic research and scientific papers

Halogen perchlorates. Additions to perhaloolefins

The recently discovered halogen perchlorates, Cl2O4 and BrClO4, have been found to react with perhaloolefins by adding across the carbon-carbon double bond. These reactions proceeded quickly at low temperatures, in the absence of a solvent, to furnish the previously unknown perhaloalkyl perchlorates in high yield. Compounds prepared in this manner were ClCF2CF2ClO4, ClCF2CFClClO4, Cl2CFCFClClO4, CF3CFClCF2ClO4, BrCF2CFClClO4, and CF3CFBrCF2ClO4. Characteristic data for these surprisingly stable compounds are reported. All the new perchlorates reacted with alkali metal fluorides to form the corresponding acid fluorides and either FClO3 or mixtures of FClO3, Cl2, and O2.

Method for synthesizing beta-halogen tetrafluoroacyl fluoride

The invention discloses a method for synthesizing beta-halogen tetrafluoroacyl fluoride. The preparation method specifically comprises the following steps: adding an alkali halide and a catalyst into a drying reactor with a dry ice reflux condenser, placing the drying reactor in an ice water bath, slowly introducing hexafluoropropylene oxide with stirring, keeping the drying reactor in the ice water bath for 2h until no reflux exists at the bottom of the dry ice reflux condenser, continuing performing stirring for 2h, separating liquid with a liquid separation funnel, performing distillation under normal pressure, introducing gas produced in a distillation process into a cold trap for collection, and transferring the gas into a steel bottle to obtain liquid beta-halogen tetrafluoroacyl fluoride. The conversion rate of the raw material and the purity of a product are high, the purity of the product subjected to fractional distillation can reach 99 percent or higher, the product can chemically react with alcohol to obtain ester with purity of 99 percent, the production steps of the preparation method are simple and safe, and the preparation method is short in reaction time and high in productivity.

Synthesis of functionalized polyfluoroalkyl hypochlorites and fluoroxy compounds and their reactions with some fluoroalkenes

Several new polyfluoroalkyl hypochlorites and fluoroxy compounds containing Cl, H and Br in the alkyl group have been prepared and characterized by 19F NMR, 1H NMR and IR spectroscopies and by their reactions with fluoroalkenes to produce new polyfluoroethers.The novel compounds are prepared by the CsF-catalyzed addition of F2 or ClF to the C=O bond in CF3C(O)CF2Cl, ClCF2C(O)CF2Cl, and their derivatives HCF2C(O)CF3 and HCF2C(O)CF2Cl.Compounds containing an α-CF3 group exhibit enhanced thermal stability.New fluoroxy compounds and hypochlorites have also been prepared from the acid fluorides CF3-CFX-C(O)F (X = Cl, Br), which are obtained by the ring-opening reaction of hexafluoropropene oxide with (CH3)3SiCl, LiBr and (C2H5)3SiBr.These -OX compounds behave similarly to previously known materials with two α-F atoms, decomposing quickly at room temperature to COF2 and haloalkanes.

IONIC TELOMERIZATION OF CHLOROFLUOROPROPIONYL FLUORIDES WITH HEXAFLUOROPROPENE OXIDE

Six chlorofluoropropionyl fluorides were synthesized by converting a -CCl3 group in perhalogenated chlorofluoropropanes to a -COF group in two reaction steps.The ionic telomerization of the acyl fluorides with hexafluoropropene oxide, catalyzed by fluoride ion, afforded mainly a mixture of 1:1 to 1:3 telomers.In some cases, substitution of chlorine for fluorine in the acyl moiety and hexafluoropropene oxide oligomerization occured as side reactions.The effect of the number of chlorines in the starting acyl fluoride on the telomer distribution and by product formation is discussed.The reactivity order of the acyl fluorides Y-COF in the telomerization reaction was: CF3-CClF (2a), CClF2-CF2 (2b) > CF3-CCl2 (3a),CClF2-CClF (3b) > CClF2-CCl2 (4a), CCl2F-CClF (4b).Possible reaction pathways are discussed.