6066-46-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Chlorotetrafluoropropanoyl chloride is used as a reagent in organic synthesis for the production of pharmaceuticals. It aids in the synthesis of various drug compounds due to its reactive nature.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Chlorotetrafluoropropanoyl chloride serves as a reagent in organic synthesis, contributing to the development of agrochemical products.
Used in Fine Chemicals Production:
2-Chlorotetrafluoropropanoyl chloride is utilized in the production of other fine chemicals, where its reactivity is key to forming desired chemical structures.
Used in Fluorinated Polymers Manufacturing:
CTFP is used as a building block in the manufacturing of fluorinated polymers, which have a range of applications due to their unique properties.
Used in Specialty Chemicals Production:
2-Chlorotetrafluoropropanoyl chloride also plays a role in the production of specialty chemicals, where its specific reactivity is required for synthesizing complex molecules.
Note: When handling 2-Chlorotetrafluoropropanoyl chloride, proper safety measures and protective equipment should be used due to its hazardous nature.

InChI:InChI=1/C3Cl2F4O/c4-1(10)2(5,6)3(7,8)9

Upstream product

• 2268-46-4 freon-214 

Downstream Products

• 28627-00-1 2,3,3,3-tetrafluoro-2-chloropropanoyl fluoride 

Relevant academic research and scientific papers

THE CHEMO-SELECTIVE REDUCTION OF FLUORINATED HALOGENOESTERS WITH SODIUM BOROHYDRIDE. FLUORINATED HALOGENOALKANOLS AND THEIR (METH)ACRYLATES

Several chlorofluoroalkanols RF-CH2OH (RF is CF3-CFCl, CF2Cl-CF2, CF2Cl-CFCl and CF2Cl) and their methacrylates or acrylates were synthesized.The corresponding polymeric methacrylates have properties of highly-sensitive electron-beam and X-ray resists for microlithography.The main step in the syntheses, which start from halogenoalkanes RF-CCl3, is the chemo-selective reduction of halogenoesters with sodium borohydride, in which the C-Cl bonds in the acyl parts of the esters are not attacked.Relative rates of the reductions of esters RF-COOCH3 are influenced by the structure of halogenoalkyls RF in the order CF2Cl: CF3-CFCl: CF2Cl-CFCl = 4.5:3.5:1.A remarkable reactivity decrease in the reduction rate in the structure possessing a Cl atom at the β-position in the acyl group is discussed.

IONIC TELOMERIZATION OF CHLOROFLUOROPROPIONYL FLUORIDES WITH HEXAFLUOROPROPENE OXIDE

Six chlorofluoropropionyl fluorides were synthesized by converting a -CCl3 group in perhalogenated chlorofluoropropanes to a -COF group in two reaction steps.The ionic telomerization of the acyl fluorides with hexafluoropropene oxide, catalyzed by fluoride ion, afforded mainly a mixture of 1:1 to 1:3 telomers.In some cases, substitution of chlorine for fluorine in the acyl moiety and hexafluoropropene oxide oligomerization occured as side reactions.The effect of the number of chlorines in the starting acyl fluoride on the telomer distribution and by product formation is discussed.The reactivity order of the acyl fluorides Y-COF in the telomerization reaction was: CF3-CClF (2a), CClF2-CF2 (2b) > CF3-CCl2 (3a),CClF2-CClF (3b) > CClF2-CCl2 (4a), CCl2F-CClF (4b).Possible reaction pathways are discussed.