28669-41-2

Basic information

• Product Name: 4-Phenyl-2-propyl-1,3,4-oxadiazol-5(4H)-one
• Synonyms: 4-Phenyl-2-propyl-1,3,4-oxadiazol-5(4H)-one
• CAS NO: 28669-41-2
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 0
• Mol File: 28669-41-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Phenyl-2-propyl-1,3,4-oxadiazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-2-propyl-1,3,4-oxadiazol-5(4H)-one(28669-41-2)
• EPA Substance Registry System: 4-Phenyl-2-propyl-1,3,4-oxadiazol-5(4H)-one(28669-41-2)

Safety Data

• Hazardous Substances Data: 28669-41-2(Hazardous Substances Data)

Upstream product

• 106-31-0 butanoic acid anhydride 
• 508191-77-3 3-phenylsydnone 
• 13183-09-0 3-phenyl-4-bromosydnone 
• 124-38-9 carbon dioxide 
• 123-72-8 butyraldehyde 
• 100-63-0 phenylhydrazine 
• 141-75-3 butyryl chloride 

Relevant articles and documents

One-pot synthesis of 1,3,4-oxadiazol-2(3H)-ones with CO2 as a C1 synthon promoted by hypoiodite

A convenient and efficient route has been developed to synthesize 1,3,4-oxadiazol-2(3H)-ones from CO2, hydrazines and aryl or aliphatic aldehydes. Promoted by hypoiodite (IO-) generated in situ from KI and oxidant TBHP, the one-pot synthesis could proceed smoothly to afford the desired products in moderate to high yields. Mechanism studies revealed that nitrile imine was an important intermediate in this transformation. Notably, a commercial herbicide Oxadiazon could be successfully synthesized by this route.