28714-28-5

Upstream product

• 711-38-6 4'-methoxy-2,2,2-trifluoroacetophenone 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 696-62-8 para-iodoanisole 
• 5720-07-0 4-methoxyphenylboronic acid 
• 692-50-2 hexafluoro-2-butyne 

Downstream Products

• 99749-13-0 4,4'-((2RS,3SR)-1,1,1,4,4,4-hexafluorobutane-2,3-diyl)bis(methoxybenzene) 
• 99749-16-3 meso-1,1,1,4,4,4-hexafluoro-2,3-bis(4-hydroxyphenyl)butane 

Relevant academic research and scientific papers

Palladium catalyzed mono and difunctionalization of hexafluorobut-2-yne

The Pd(0) catalyzed one-pot mono and difunctionalization of hexafluorobut-2-yne is investigated. Styrenes and stilbenes can be obtained in high stereoselectivity by carbopalladation of phenylboronic acids and iodide benzenes. The reactions afford a facile access to a broad scope with good functional compatibility.

Influence of Alkyl-Chain Fluorination on the Action of Mammary Tumor Inhibiting 2,3-Bis(hydroxyphenyl)butanes and 2,3-Bis(hydroxyphenyl)but-2-enes

trans-1,2-Bis(trifluoromethyl)-1,2-bis(4- and 3-hydroxyphenyl)ethenes 2 and 4 were prepared by reductive coupling (TiCl4/Zn/pyridine) of the methoxy-substituted α,α,α-trifluoroacetophenones, separation of the resulting cis- and trans-stilbene derivatives,