287384-12-7

Usage

Uses

Used in Pharmaceutical Synthesis:
(S,S)-3,4,5-Trifluorophenyl-NAS bromide is used as a building block for the development of pharmaceuticals, leveraging its reactivity and stability to create complex molecular structures that can be tailored for specific therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, (S,S)-3,4,5-Trifluorophenyl-NAS bromide is used as a precursor for the synthesis of various agrochemicals, taking advantage of its potential to introduce fluorine atoms into organic molecules and enhance their biological properties.
Used in Asymmetric Synthesis:
(S,S)-3,4,5-Trifluorophenyl-NAS bromide is utilized as a component in the preparation of ligands and chiral catalysts for asymmetric synthesis, a crucial technique in creating enantiomerically pure compounds with improved selectivity and reactivity.
Used in Organic Synthesis:
(S,S)-3,4,5-TRIFLUOROPHENYL-NAS BROMIDE is employed as a versatile building block in organic synthesis, where its trifluorophenyl group and bromide atom facilitate various chemical reactions and derivatization processes, contributing to the creation of diverse organic molecules with specific properties and applications.

Upstream product

• 97551-09-2 (S)-4,5-dihydro-3H-dinaphtho[2,1-c:1′,2′-e]azepine 
• 143418-49-9 3,4,5-trifluorophenylboronic acid 
• 37803-02-4 (S)-2,2'-bis(bromomethyl)-1,1'-binaphthyl 

Relevant academic research and scientific papers

Improved access to chiral tetranaphthoazepinium-based organocatalysts using aqueous ammonia as nitrogen source

The class of 3,30-diaryl substituted tetranaphthobisazepinium bromides has found wide application as highly efficient C2-symmetrical phase-transfer catalysts (PTCs, Maruoka type catalysts). Unfortunately, the synthesis requires a lar

New, improved procedure for the synthesis of structurally diverse N-spiro C2-symmetric chiral quaternary ammonium bromides

Selective, direct ortho magnesiation of (S)-2,2′bis(isopropoxycarbonyl)-1,1′-binaphthyl (6) has been achieved under mild conditions, using magnesium bis(2,2,6,6-tetramethylpiperamide) [Mg(TMP)2]. In combination with the subsequent reaction with

Design of N-spiro C2-symmetric chiral quaternary ammonium bromides as novel chiral phase-transfer catalysts: Synthesis and application to practical asymmetric synthesis of α-amino acids

A series of C2-symmetric chiral quaternary ammonium bromides 10 and 11 have been designed as a new, purely synthetic chiral phase-transfer catalyst, and readily prepared from commercially available optically pure 1,1′-bi-2-naphthol as a basic c

Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and application thereof for asymmetric synthesis of α-amino acid

A novel optically active quarternary ammonium salt with an axial chirality is provided. The quarternary ammonium salt can act as a phase-transfer catalyst to convert glycine derivatives into optically active α-amino acid derivatives by stereoselectively a