287953-54-2

Usage

Uses

Used in Pharmaceutical and Biochemical Research:
N-Benzyloxycarbonyl-4-piperidinesulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence in chemical reactions facilitates the creation of complex organic molecules, which are crucial for the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
In the realm of organic chemistry, N-Benzyloxycarbonyl-4-piperidinesulfonyl chloride is used as a reagent in the formation of new chemical bonds and the synthesis of complex organic molecules. Its role in these reactions is essential for advancing the field and discovering new chemical entities.
Used in Peptide Synthesis:
Due to the presence of the benzyloxycarbonyl protective group, N-Benzyloxycarbonyl-4-piperidinesulfonyl chloride is used as a protecting agent in peptide synthesis. This group helps prevent unwanted side reactions during the synthesis process, ensuring the formation of the desired peptide sequence.

InChI:InChI=1/C13H16ClNO4S/c14-20(17,18)12-6-8-15(9-7-12)13(16)19-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2

Upstream product

• 146827-60-3 4-(acetylthio)-1-(benzyloxycarbonyl)piperidine 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 199103-19-0 benzyl 4-[(methylsulfonyl)oxy]piperidine-1-carboxylate 
• 95798-23-5 1-(benzyloxycarbonyl)-4-hydroxypiperidine 
• 166953-64-6 benzyl 4-bromo-1-piperidinecarboxylate 
• 90633-18-4 4-bromo-1H-piperidine 

Downstream Products

• 622386-76-9 C₂₉H₄₀N₂O₄S 
• 622386-85-0 C₂₈H₃₈N₂O₅S 
• 622387-28-4 benzyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1-carboxylate 
• 878388-35-3 benzyl 4-sulfamoylpiperidine-1-carboxylate 
• 1246203-81-5 benzyl 4-[(methylamino)sulfonyl]-1-piperidinecarboxylate 
• 1246203-83-7 benzyl 4-[[[2-(dimethylamino)ethyl]amino]sulfonyl]-1-piperidinecarboxylate 
• 1426154-26-8 benzyl 4-({[2-chloro-6-(morpholin-4-yl)pyrimidin-4-yl]methyl}sulfonyl)piperidine-1-carboxylate 
• 1616974-33-4 sodium 1-[(benzyloxy)carbonyl]piperidine-4-sulfinate 
• 1428973-10-7 benzyl 4-((3-(2-chloro-2-phenylacetyl)-1H-indol-1-yl)sulfonyl)piperidine-1-carboxylate 
• 1312592-79-2 phenylmethyl 4-chloro-4-[({2,6-dimethyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}amino)sulfonyl]-1-piperidinecarboxylate 
• 1344125-12-7 C₂₆H₃₃N₅O₄S₂ 
• 1196150-83-0 4-(1-Hydroxy-1,3-dihydro-benzo[c][1,2]oxaborol-6-ylsulfamoyl)-piperidine-1-carboxylic acid benzyl ester 
• 1083326-06-0 benzyl 4-[(dimethylamino)sulfonyl]-1-piperidinecarboxylate 
• 1035173-67-1 benzyl 4-[[5-[4-(4-cyanophenyl)piperidine-1-carbonyl]-2-methyl-phenyl]-[(2-methylpropan-2-yl)oxycarbonyl]sulfamoyl]piperidine-1-carboxylate 

Relevant academic research and scientific papers

NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS

The present invention relates to compounds of formula (I) wherein Q is selected from O or S; R1 is a non-aromatic heterocyclic group comprising at least one ring nitrogen atom, wherein R1 is attached to the sulfur atom of the sulfonylurea group by a ring carbon atom, and wherein R1 may optionally be substituted; and R2 is a cyclic group substituted at the α-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

A library of conformationally restricted saturated heterocyclic sulfonyl chlorides

An approach to the synthesis of conformationally restricted saturated heterocyclic sulfonyl chlorides is described. Being guided by the principle of diversity-oriented conformational restriction, a mini-library of saturated heterocyclic sulfonyl chlorides

1-(4-PIPERIDINYL) BENZIMIDAZOLONES AS HISTAMINE H3 ANTAGONISTS

Disclosed are histamine H3 antagonists of the formula (I) wherein R1 is benzimidazolone derivative, M1 and M2 are optionally substituted carbon or nitrogen, R2 includes optionally substituted aryl or heteroaryl, and the remaining variables are as defined