288104-74-5Relevant academic research and scientific papers
Novel pyrazole-3-carboxamide derivatives as cannabinoid-1 (CB1) antagonists: Journey from non-polar to polar amides
Sasmal, Pradip K.,Reddy, D. Srinivasa,Talwar, Rashmi,Venkatesham,Balasubrahmanyam,Kannan,Srinivas,Kumar, K. Shiva,Devi, B. Neelima,Jadhav, Vikram P.,Khan, Sanjoy K.,Mohan, Priya,Chaudhury, Hira,Bhuniya, Debnath,Iqbal, Javed,Chakrabarti, Ranjan
scheme or table, p. 562 - 568 (2011/02/25)
The synthesis and biological evaluation of novel pyrazole-3-carboxamide derivatives as CB1 antagonists are described. As a part of eastern amide SAR, various chemically diverse motifs were introduced. In general, a range of modifications were well tolerat
Imidazol-4-one and Imidazole-4-thione Compounds
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Page/Page column 15, (2010/05/13)
Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
Pyrazolecarboxylic acid derivatives, their preparation, pharmaceutical compositions containing them
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, (2008/06/13)
N-Piperidino-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxamide and its salts and solvates are powerful antagonists of the CB1cannabinoid receptors. They are prepared by reacting a functional derivative of 5-(4-bromophenyl)-
