288141-85-5

Upstream product

• 60-12-8 2-phenylethanol 
• 219547-77-0 t-butyl 3-(trichloromethyl)-1,2-oxaziridine-2-carboxylate 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 4732-11-0 O-(2-phenylethyl)hydroxylamine 

Relevant academic research and scientific papers

Synthesis of O-alkylhydroxylamines by electrophilic amination of alkoxides

The 3-trichloromethyloxaziridine 7 reacts smoothly with lithium alkoxides, derived from a representative range of alcohols, transferring an NHBoc function to the oxygen to provide good to excellent yields of N-Boc-O- alkylhydroxylamines 8-16 by this new O-amination protocol.

3,6-Bicyclolides

The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.