28837-74-3Relevant academic research and scientific papers
3-SUBSTITUTED-1H-INDOLE, 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
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Page/Page column 99-100, (2010/04/06)
The invention relates to 3-substituted-1H-indole, 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula (I): or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
DNA Intercalating Compounds as Potential Antitumor Agents. 1. Preparation and Properties of 7H-Pyridocarbazoles
Pelaprat, Didier,Oberlin, Robert,Le Guen, Irene,Roques, Bernard P.,Pecq, Jean-Bernard Le
, p. 1330 - 1335 (2007/10/02)
The DNA Intercalating compounds derived from 6H-pyridocarbazole (ellipticines, olivacines) elicit high antitumor properties.In order to get information about the mechanism of action of these agents it is necessary to study structurally related analogues.F
