Indole-2-carboxamide, N,N-dimethyl-5-methoxy-

Base Information

Chemical Name:Indole-2-carboxamide, N,N-dimethyl-5-methoxy-
CAS No.:28837-74-3
Molecular Formula:C₁₂H₁₄N₂O₂
Molecular Weight:218.255
Hs Code.:
NSC Number:357595
DSSTox Substance ID:DTXSID20183026
Wikidata:Q83053750
Mol file:28837-74-3.mol

Synonyms:Indole-2-carboxamide, N,N-dimethyl-5-methoxy-;28837-74-3;5-methoxy-N,N-dimethyl-1H-indole-2-carboxamide;BRN 0398307;N,N-Dimethyl-5-methoxyindole-2-carboxamide;NSC357595;SCHEMBL1428560;DTXSID20183026;SYUDWKXSBCRQMN-UHFFFAOYSA-N;STK266725;AKOS005424592;NSC 357595;NSC-357595;5-methoxy-indole-2-carboxylic acid dimethylamide;Z1509161888

Suppliers and Price of Indole-2-carboxamide, N,N-dimethyl-5-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Indole-2-carboxamide, N,N-dimethyl-5-methoxy-

Chemical Property:

Vapor Pressure:1.36E-07mmHg at 25°C
Boiling Point:429.8°Cat760mmHg
Flash Point:213.8°C
Density:1.204g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:268

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=CC2=C(N1)C=CC(=C2)OC

Technology Process of Indole-2-carboxamide, N,N-dimethyl-5-methoxy-

There total 4 articles about Indole-2-carboxamide, N,N-dimethyl-5-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 4382-54-1
5-methoxy-1H-indole-2-carboxylic acid

: 124-40-3
dimethyl amine

: 28837-74-3
N,N-dimethyl-5-methoxyindole-2-carboxamide

Guidance literature:: 5-methoxy-1H-indole-2-carboxylic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 0 ℃;

dimethyl amine; In tetrahydrofuran; dichloromethane; at 20 ℃; Sealed tube;

Reference yield:

: 4382-54-1
5-methoxy-1H-indole-2-carboxylic acid

: 28837-74-3
N,N-dimethyl-5-methoxyindole-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / benzene / 5.92 h / 20 - 55 °C

2: benzene; diethyl ether / Ambient temperature

With thionyl chloride; In diethyl ether; benzene;
DOI:10.1021/jm00186a009