288395-80-2Relevant articles and documents
Studies on the narciclasine alkaloids: Total synthesis of (+)- narciclasine and (+)-pancratistatin
Rigby, James H.,Maharoof, Umar S. M.,Mateo, Mary E.
, p. 6624 - 6628 (2007/10/03)
Enantioselective total syntheses of the antimmor alkaloids, (+)- narciclasine and (+)-pancratistatin, are reported. These syntheses feature a stereo- and regiocontrolled aryl enamide photocyclization to construct a common, advanced intermediate possessing a transfused BC substructure. Differential functional group interchange in the C-ring of this phenanthridone core structure allows for the production of the two target natural products in enantiomerically pure form.