28840-96-2 Usage
Type
Naturally occurring steroid hormone
Production
Produced in the adrenal glands and gonads
Role
Precursor to sex hormones testosterone and estrogen
Function
Plays a key role in the body's endocrine system
Potential Applications
Studied for use in the treatment of hormone-related conditions such as breast and prostate cancer
Performance Enhancement
Studied in the development of performance-enhancing drugs
Mechanism of Action
Acts as an aromatase inhibitor, inhibiting the conversion of androgens to estrogens
Effects
Has been shown to have anti-estrogenic effects in some studies
Research Status
More research is needed to fully understand the potential therapeutic applications and side effects of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 28840-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,8,4 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 28840-96:
(7*2)+(6*8)+(5*8)+(4*4)+(3*0)+(2*9)+(1*6)=142
142 % 10 = 2
So 28840-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H24O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(21)19(14,2)17(22)10-15(13)18/h7-9,13-15,17,22H,3-6,10H2,1-2H3/t13-,14-,15-,17?,18-,19-/m0/s1
28840-96-2Relevant articles and documents
Raspe,Kieslich
, p. 479 (1961)
MICROBIAL DEGRADATION OF DEOXYCHOLIC ACID BY PSEUDOMONAS sp. NCIB 10590. CHARACTERISATION OF PRODUCTS AND A POSTULATED PATHWAY
Bilton, R. F.,Mason, A. N.,Tenneson, M. E.
, p. 2509 - 2514 (2007/10/02)
Minor products in the microbial degradation of deoxychlolic acid are characterised and a metabolic pathway proposed.In a previous publocation we reported the transformation of deoxycholic acid 1 by Pseudomonas sp.NCIB 10590, in a mineral salts medium, to a mixture of neutral and acidic steroids.The major neutral product, 12β-hydroxyandrosta-1,4-dien-3,17-dione 2 and the major acidic product 12α-hydroxypregna-1,4-dien-3-one-20-carboxylic acid 9 were identified.We now report the structures of the minor products and propose a metabolic pathway.
