288582-12-7

Upstream product

• 30093-99-3 4,4-dimethyl-2-oxazoline 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 668988-24-7 N-((1-phenoxycarbonyloxy-2-methylpropan-2-ylcarbamoyl)-1-phenylmethyl)-N-phenylbenzamide 
• 668988-21-4 N-((1-phenoxycarbonyloxy-2-methylpropan-2-ylcarbamoyl)-1-phenylmethyl)-N-benzylbenzamide 
• 668988-20-3 N-(1-(1-phenoxycarbonyloxy-2-methylpropan-2-ylcarbamoyl)ethyl)-N-benzylbenzamide 
• 668988-22-5 N-(2-methyl-1-(1-phenoxycarbonyloxy-2-methylpropan-2-ylcarbamoyl)propyl)-N-benzylacetamide 
• 668988-19-0 N-((1-phenoxycarbonyloxy-2-methylpropan-2-ylcarbamoyl)methyl)-N-benzylbenzamide 
• 668988-29-2 N-(1-(4,4-dimethyl-2-oxo-3-oxazolidinyl)carbonyl-2-methylpropyl)-N-benzylacetamide 

Relevant academic research and scientific papers

A Versatile Synthesis of α-Amino Acid Derivatives via the Ugi Four-Component Condensation with a Novel Convertible Isonitrile

The Ugi four-component condensation (4CC) reaction with the carbonate-type isonitrile 9 proceeded smoothly, and subsequent base treatment of the Ugi products 10 provided the N-acyloxazolidinones 11 in high yield. The N-acyloxazolidinones derivatives can be reacted with several hetero-nucleophiles, namely, reaction of 11 with thiolates gave thiol ester derivatives 16 efficiently.

A versatile synthesis of α-amino acid derivatives via the ugi four-component condensation with a novel convertible isonitrile

The Ugi four-component condensation (4CC) reaction with the carbonate-type isonitrile 9 proceeded smoothly, and subsequent base treatment of the Ugi products 10 provided the N-acyloxazolidinones 11 in high yield. The N-acyloxazolidinone derivatives can be reacted with several hetero-nucleophiles, namely, reaction of 11 with thiolates gave thiol ester derivatives 16 efficiently.