80483-99-4Relevant academic research and scientific papers
A New Thermal Rearrangement in the 4-Isoxazoline System. Some Chemical and Stereochemical Properties of a Benzodiazepine Oxide-Ethyl Propiolate Adduct
Freeman, Jeremiah P.,Duchamp, David J.,Chidester, Constance G.,Slomp, George,Szmuszkovicz, Jacob,Raban, M.
, p. 1380 - 1386 (2007/10/02)
Reaction of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 4 oxide, 3, with ethyl propiolate afforded the expected 4-isoxazoline 4 and a rearangement product 5.Product 5 and a further rearrangement product, 6, could be obtained from 4 u
