2893-48-3

Basic information

• Product Name: 2-(N-METHYL-N-BUTYLAMINO)ETHANOL
• Synonyms: N-BUTYL-N-METHYLETHANOLAMINE;2-(N-METHYL-N-BUTYLAMINO)ETHANOL;2-[butyl(methyl)amino]ethanol;N-n-Butyl-N-MethylethanolaMine, 96%
• CAS NO: 2893-48-3
• Molecular Formula: C₇H₁₇NO
• Molecular Weight: 131.22
• Mol File: 2893-48-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 187℃
• Flash Point: 57°(135°F)
• Appearance: /
• Density: 0.88
• Sensitive: Hygroscopic
• CAS DataBase Reference: 2-(N-METHYL-N-BUTYLAMINO)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-METHYL-N-BUTYLAMINO)ETHANOL(2893-48-3)
• EPA Substance Registry System: 2-(N-METHYL-N-BUTYLAMINO)ETHANOL(2893-48-3)

Safety Data

• HazardClass: 3
• Hazardous Substances Data: 2893-48-3(Hazardous Substances Data)

Usage

General Description

2-(N-methyl-N-butylamino)ethanol is a chemical compound that is used as a surfactant in the formulation of cleaning products and personal care items. It is a clear, colorless liquid with a mild odor and is soluble in water. This chemical is known for its ability to effectively remove dirt, grease, and oil from surfaces, making it a common ingredient in detergents, degreasers, and industrial cleaning solutions. It is also used in personal care products such as shampoos and soaps for its emulsifying and cleansing properties. Additionally, 2-(N-methyl-N-butylamino)ethanol is considered to be relatively safe for use, as it is not known to be toxic or harmful to humans when used as directed.

Upstream product

• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 542-69-8 1-iodo-butane 
• 1630-74-6 3-butyl-1,3-oxaazacyclopentane 
• 109-65-9 1-bromo-butane 
• 1630-76-8 3-methyl-2-propyloxazolidine 
• 64-17-5 ethanol 

Relevant articles and documents

pH-Sensitive Polycations for siRNA Delivery: Effect of Asymmetric Structures of Tertiary Amine Groups

pH-sensitive polyelectrolytes provide enormous opportunity for siRNA delivery. Especially, their tertiary amine structures can not only bind genes but also act as pH-sensitive hydrophobic structure to control genes release. However, the influence of molecular structures on siRNA delivery still remains elusive, especially for the asymmetric alkyl substituents of the tertiary amine groups. Herein, a library of N-methyl-N-alkyl aminoethyl methacrylate monomers (MsAM) with asymmetric alkyl substituents on the tertiary amine group is synthesized and used to prepare a series of tri-block polycationic copolymers poly(aminoethyl methacrylate)-block-poly (N-methyl-N-alkyl aminoethyl methacrylate)-block-poly(ethylene glycol methacrylate) (PAMA-PMsMA-PEG). And the properties of these polycations and their self-assembled micelles are characterized, including molecular structure, proton buffering capacity, pH-sensitivity, size, and zeta potential. With the length increase of one alkyl substituent, the proton buffering capacity of both monomers and polycations is demonstrated to be narrowed down. The siRNA delivery efficiency and cytotoxicity of these micelles are also evaluated on HepG2 cells. In particular, poly(aminoethyl methacrylate)-block-poly(N-methyl-N-ethyl aminoethyl methacrylate)-block-poly(ethylene glycol methacrylate) (PAMA-PMEMA-PEG) elicited the best luciferase knockdown efficiency and low cytotoxicity. Besides, PAMA-PMEMA-PEG/siRRM2 also induced significant anti-tumor activity in vitro. These results indicated PAMA-PMEMA-PEG has potential for further use in the design of gene vehicles with the improved efficiency of siRNA delivery.

STRUCTURE OF PRODUCTS AND PARTIAL CHAIN TRANSFER CONSTANTS IN THE RADICAL TELOMERIZATION OF ETHYLENE WITH 3-BUTYL-1,3-OXAZOLIDINE

The radical telomerization of ethylene with 3-butyl-1,3-oxazolidine, initiated by tert-butyl peroxide, at 140 deg C leads to the formation of telomeric N-butyl-N-alkylformamides.The partial chain transfer constants were determined for the growing telomeric radicals.