289480-96-2

Basic information

• Product Name: (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide)
• Synonyms: (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide)
• CAS NO: 289480-96-2
• Molecular Weight: 434.582
• Mol File: 289480-96-2.mol

Chemical Properties

• CAS DataBase Reference: (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide)(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide)(289480-96-2)
• EPA Substance Registry System: (2S,2'S)-N,N'-(ethane-1,2-diyl)bis(1-benzylpyrrolidine-2-carboxamide)(289480-96-2)

Safety Data

• Hazardous Substances Data: 289480-96-2(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 497818-56-1 C₂₂H₃₈N₄O₆ 
• 102981-31-7 N,N'-bis[(S)-N-benzyloxycarbonylprolyl]-1,2-ethylenediamine 
• 100-39-0 benzyl bromide 
• 54985-58-9 N,N'-bis[(S)-prolyl]-1,2-ethylenediamine 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 289480-97-3 N,N'-bis{[(S)-N-benzyl-pyrrolidin-2-yl]methyl}ethylenediamine 

Relevant articles and documents

Synthesis and structure of a novel tridentate chiral-NHC ligand precursor

A novel tridentate chiral imidazolium hexafluorophosphate, a precursor for N-heterocyclic carbene (NHC) ligand, was synthesized from (S)-proline in five steps in 24 % overall yield. The compound was characterized by NMR and elemental analysis. Its molecular structure was determined by X-ray diffraction analysis. This chiral compound has two stereogenic centers which are within two chelating side chains and its specific rotation is-19.6°. 2011 · Copyright by Walter de Gruyter.

Rh and Ir complexes containing multidentate, C2-symmetry ligands. Structural and catalytic properties in asymmetric hydrogenation

A comparative investigation of the interaction of Rh(I) and Ir(I) with a series of mixed-donor multidentate, C2-symmetry ligands has been carried out. The complexes have been prepared by the reaction of [MCl(cod)]2 (cod=1,5-cyclooctadiene) with AgPF6 and further treatment with the ligand. All ligands form 1:1 (metal:ligand) species with the above metal ions although, in a few instances, species of type [M2L2]2+ were also detected. The structures of these complexes were elucidated by analytical and spectroscopic data (elemental analysis, mass spectroscopy, IR, 1H- and 13C-NMR). Complexes were tested in the asymmetric hydrogenation of prochiral olefins, providing enantioselectivities up to 36%.