2898-20-6Relevant academic research and scientific papers
Design, synthesisand preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring
Guandalini,Balliu,Cellai,Martino,Nebbioso,Mercurio,Carafa,Bartolucci,Dei,Manetti,Teodori,Scapecchi,Altucci,Paoletti,Romanelli
, p. 56 - 68 (2013/10/01)
A series of new histone deacetylase inhibitors were designed and synthesized based on hybridization between SAHA or oxamflatin and 5-phenyl-1,4-benzodiazepines. The compounds were tested for their enzyme inhibitory activity on HeLa nuclear extracts, and o
CHEMICAL COMPOUNDS
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Page/Page column 50, (2008/06/13)
The present invention relates to dihydrobenzodiazepine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such dihydrobenzodiazepine derivatives
