28987-50-0

Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-4-isopropoxy-1-nitrobenzene is used as a chemical intermediate for the synthesis of pharmaceuticals. Its unique functional groups allow for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Fluoro-4-isopropoxy-1-nitrobenzene serves as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals.
Used in Dye Manufacturing:
2-Fluoro-4-isopropoxy-1-nitrobenzene is utilized in the manufacturing of dyes due to its chemical properties that can be incorporated into dye molecules to produce a range of colors.
Used in Perfume Production:
2-Fluoro-4-isopropoxy-1-nitrobenzene is also used in the production of perfumes, where its chemical structure can contribute to the creation of unique and complex fragrances.
Used in Organic Compound Synthesis:
2-Fluoro-4-isopropoxy-1-nitrobenzene is employed as a building block in the synthesis of various organic compounds, expanding the range of possible chemical products.
Safety Note:
Due to the presence of nitro and fluoro functional groups, 2-Fluoro-4-isopropoxy-1-nitrobenzene has the potential to be hazardous if not handled properly. It should be stored and used with caution in a controlled laboratory setting or industrial environment to ensure safety.

Upstream product

• 75-30-9 2-iodo-propane 
• 446-38-8 2-fluoro-4-methoxy-1-nitro-benzene 
• 394-41-2 3-fluoro-4-nitrophenol 
• 67-63-0 isopropyl alcohol 
• 446-35-5 2,4-Difluoronitrobenzene 
• 6831-82-9 potassium isopropoxide 
• 683-60-3 sodium isopropylate 

Downstream Products

• 932701-01-4 1,1-dimethylethyl 4-({5-[(1-methylethyl)oxy]-2-nitrophenyl}amino)-1-piperidinecarboxylate 
• 154080-04-3 2-fluoro-4-isopropoxyaniline 

Relevant academic research and scientific papers

BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT Ml RECEPTOR

Compounds of formula (I) and salts and solvates are provided: wherein R6 is selected from hydrogen, halogen, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6 alkoxy, C1-6 alkoxy substituted with one or more fluorine atoms, and cyano, and Q is hydrogen or C1-6alkyl. The compounds are M1 agonists and are useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.

Herbicical 2-[(4-heterocyclic-phenoxymethyl)phenoxy]-alkanoates

Herbicidal compounds, compositions containing them, and a method for controlling weeds by application of the compositions are disclosed. The herbicidal compounds are 2-[(4-heterocyclic(phenoxymethyl)phenoxy]alkanoates of the formula STR1 in which A is a derivative of an alkanoate bonded to the phenoxy oxygen at the alpha carbon, and Q is 4-difluoromethyl-4,5-dihydro-3-methyl-1,2,4-triazol-5(1H)-on-1-yl, 3,4,5,6-tetrahydrophthalimid-1-yl, 1-(1-methylethyl)imidazolidin-2,4-dion-3-yl, 1,4-dihydro-4-(3-fluoropropyl)-5H-tetrazol-5-on-1-yl, 3-chloro-4,5,6,7-tetrahydroindazol-2-yl, 4-methyl-1,2,4-triazine-3,5-dion-2-yl, 8-thia-1,6-diazabicyclo[4.3.0]nonane-7-on-9-ylimino, or 1-methyl-6-trifluoromethyl-2,4-pyrimidinedione-3-yl; X is hydrogen, fluorine, or chlorine; Y is hydrogen; W is oxygen or sulfur; Z is hydrogen, fluorine, chlorine, bromine, lower alkyl, or methoxy; Z' is hydrogen, fluorine, or chlorine; and the group AO-- may be in the 2, 3, or 4-position of the phenyl ring.

REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. VI. ORIENTATION IN THE REACTIONS OF 2,4-DIFLUORONITROBENZENE WITH ALKALI-METAL ALCOHOLATES AND PHENOLATES

On the basis of the results from a study of the orientation during the substitution of a fluorine atom in 2,4-difluoronitrobenzene by the action of nucleophiles of the ROM type (R = Me, Et, i-Pr, Ph; M = Na, K) and its temperature dependence for the reactions with sodium methoxide and sodium phenolate in liquid ammonia at -70 to -33 deg C it was shown that the enthalpy control of the ratio of the substitution rates of the fluorine atoms at the ortho and para positions to the nitro group, which was previously found in the reactions of o- and p-fluoronitrobenzenes with sodium methoxide in liquid ammonia, is general.It was shown that the preference for substitution at the ortho position under these conditions increases with change in the nature of the alcoholate in the order MeO- - -.This is evidently due primarily to the increase in the polarizability of the alkyl group of alcoholate in the same order.