2899-07-2

Basic information

• Product Name: Cbz-N-methyl-L-phenylalanine
• Synonyms: N-ALPHA-CBZ-N-ALPHA-METHYL-L-PHENYLALANINE;N-ALPHA-CARBOBENZOXY-N-ALPHA-METHYL-L-PHENYLALANINE;N-CBZ-N-METHYL-L-PHENYLALANINE;Z-N-METHYL-L-PHENYLALANINE;Z-MEPHE-OH;Z-N-ME-PHENYLALANINE;Z-N-ME-PHE-OH;CBZ-N-ME-PHE-OH
• CAS NO: 2899-07-2
• Molecular Formula: C₁₈H₁₉NO₄
• Molecular Weight: 313.35
• Product Categories: N-Methyl Amino Acids;Amino Acid Derivatives
• Mol File: 2899-07-2.mol

Chemical Properties

• Melting Point: 67.0 to 71.0 °C
• Boiling Point: 484.96 °C at 760 mmHg
• Flash Point: 247.095 °C
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 3.23E-10mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: Store at RT.
• CAS DataBase Reference: Cbz-N-methyl-L-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-N-methyl-L-phenylalanine(2899-07-2)
• EPA Substance Registry System: Cbz-N-methyl-L-phenylalanine(2899-07-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 2899-07-2(Hazardous Substances Data)

Usage

Uses

Used in Biochemical Research:
Cbz-N-methyl-L-phenylalanine is used as a reagent for facilitating controlled peptide synthesis. It is essential in the process of creating specific peptide sequences by preventing unwanted side reactions, thereby ensuring the accuracy and purity of the synthesized peptides.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Cbz-N-methyl-L-phenylalanine is used as a building block for the synthesis of complex molecules, including potential drug candidates. Its role in peptide synthesis allows for the creation of novel compounds with therapeutic potential, contributing to the development of new medications.
Used in Academic Laboratories:
Cbz-N-methyl-L-phenylalanine is used as an educational tool in academic settings, where students and researchers learn about the principles of organic synthesis and peptide chemistry. It serves as a practical example of how protecting groups and amino acid modifications can be used to control reaction outcomes in the synthesis of biologically relevant molecules.

InChI:InChI=1/C18H19NO4/c1-19(18(22)23-13-15-10-6-3-7-11-15)16(17(20)21)12-14-8-4-2-5-9-14/h2-11,16H,12-13H2,1H3,(H,20,21)/t16-/m0/s1

Upstream product

• 2566-30-5 N-Methyl-L-phenylalanine 
• 501-53-1 benzyl chloroformate 
• 55740-07-3 (4S)-4-benzyl-5-oxo-1,3-oxazolidine-3-carboxylic acid benzyl ester 
• 1161-13-3 N-Cbz-L-Phe 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 24164-73-6 methyl (S)-2-(benzyloxycarbonyl-methyl-amino)-3-phenylpropionate 
• 35909-92-3 N-carbobenzoxy-L-phenylalanine methyl ester 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 15058-52-3 benzyl hydroxy(methyl)carbamate 
• 104-53-0 3-phenyl-propionaldehyde 
• 1448581-73-4 benzyl 2,4-dinitrophenylsulfonyloxy(methyl)carbamate 
• 50-00-0 formaldehyd 

Downstream Products

• 17191-53-6 Cbz-(NMe)Phe-NH₂ 
• 24164-73-6 methyl (S)-2-(benzyloxycarbonyl-methyl-amino)-3-phenylpropionate 
• 114525-93-8 Cbz-(Me)Phe-Ot-Bu 
• 192064-88-3 (S)-2-[(S)-2-(Benzyloxycarbonyl-methyl-amino)-3-phenyl-propionylamino]-3-(1H-imidazol-4-yl)-propionic acid methyl ester 
• 201408-95-9 (S)-2-[(S)-2-(Benzyloxycarbonyl-methyl-amino)-3-phenyl-propionylamino]-3-(3-trityl-3H-imidazol-4-yl)-propionic acid methyl ester 
• 202134-42-7 (2S)-benzyl 1-hydroxy-3-phenylpropan-2-yl(methyl)carbamate 
• 180597-97-1 4-benzyl-3-methoxazolidine-2,5-dione 
• 603121-69-3 benzyl (1S)-1-benzyl-2-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-oxoethyl(methyl)carbamate 
• 2566-30-5 N-Methyl-L-phenylalanine 
• 927438-78-6 2-[2-(benzyloxycarbonyl-methyl-amino)-3-phenyl-propionylamino]-3-methyl-butyric acid tert-butyl ester 
• 845777-63-1 (S)-2-[Methyl-((S)-3-methyl-2-methylamino-butyryl)-amino]-3-phenyl-propionic acid tert-butyl ester 
• 909546-90-3 HO-Lac-(Me)Val-(Me)Phe-Ot-Bu 
• 909546-88-9 Cbz-(Me)Val-(Me)Ph-Ot-Bu 
• 909546-89-0 BnO-Lac-(Me)Val-(Me)Phe-Ot-Bu 

Relevant articles and documents

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