289900-49-8Relevant academic research and scientific papers
An efficient strategy for the synthesis of α,α'-cis and trans- disubstituted medium ring ethers
Crimmins, Michael T.,Emmitte, Kyle A.
, p. 899 - 903 (2007/10/03)
An asymmetric alkylation-ring-closing metathesis strategy was developed for the construction of α,α'-disubstituted medium ring ethers. The approach features an asymmetric alkylation of highly functionalized α-alkoxy acyl oxazolidinones followed by ring closure effected by Grubbs' ruthenium catalyst. The relationship between diene conformation and the rate of ring- closure was examined.
Diastereoselective alkylations of oxazolidinone glycolates: A useful extension of the Evans asymmetric alkylation
Crimmins, Michael T.,Emmitte, Kyle A.,Katz, Jason D.
, p. 2165 - 2167 (2007/10/03)
matrix presented The diastereoselective alkylation of glycolate oxazolidinones has been demonstrated as a method for the enantioselective preparation of α-alkoxy carboxylic acid derivatives and selectively protected 1,2-diols. Various protecting groups on
