289916-26-3

Upstream product

• 67629-62-3 methyl 4-(diethylphosphono)crotonate 
• 459-57-4 4-fluorobenzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 149777-84-4 4,4,5,5-tetramethyl-2-[(E)-2-p-tolylethenyl]-1,3,2-dioxaborolane 
• 504433-86-7 2-[(1E)-2-(4-fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 623-43-8 crotonic acid methyl ester 

Downstream Products

• 203722-38-7 5-(4-fluorophenyl)penta-(2E,4E)-dienoic acid 
• 443360-61-0 (2E,4E)-5-(4-Fluoro-phenyl)-penta-2,4-dienoyl chloride 

Relevant academic research and scientific papers

TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME

The present invention relates to the treatment of disorders associated with oxidative stress including neuropathic pain and small synthetically derived compounds for treating such disorders.

Ruthenium-Catalyzed Oxidative Cross-Coupling Reaction of Activated Olefins with Vinyl Boronates for the Synthesis of (E, E)-1,3-Dienes

An oxidative cross-coupling reaction between activated olefins and vinyl boronate derivatives has been developed for the highly stereoselective construction of synthetically useful (E,E)-1,3-dienes. The highlight of this reaction is that exclusive stereoselectivity (only E,E-isomer) was achieved from a base-free, ligand-free, and mild catalytic condition with a less expensive [RuCl2(p-cymene)]2 catalyst.

Synthetic and spectroscopic studies of structural analogs of piper amides - The 5-aryl-2E,4E-pentadienamides

The methyl esters and piperidides of fourteen 5-aryl-2E,4E-pentadienoic acids have been synthesized starting from the corresponding aryl aldehydes.