2901-28-2

Basic information

• Product Name: ethyl 2-phenylhexanoate
• CAS NO: 2901-28-2
• Molecular Formula: C₁₄H₂₀O₂
• Molecular Weight: 220.3074
• Mol File: 2901-28-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 287.7°C at 760 mmHg
• Flash Point: 102°C
• Density: 0.976g/cm³
• Vapor Pressure: 0.00245mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: ethyl 2-phenylhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-phenylhexanoate(2901-28-2)
• EPA Substance Registry System: ethyl 2-phenylhexanoate(2901-28-2)

Safety Data

• Hazardous Substances Data: 2901-28-2(Hazardous Substances Data)

Usage

General Description

Ethyl 2-phenylhexanoate, also known as ethyl isovalerate, is a chemical compound commonly used in the fragrance and flavor industries. It is a clear liquid with a sweet, fruity aroma reminiscent of apple and pear. Ethyl 2-phenylhexanoate is often used as a flavoring agent in food products, such as baked goods, confectionery, and beverages. It is also used in the production of perfumes and cosmetics for its pleasant scent. Additionally, this chemical is used as a metalworking fluid, lubricant, and solvent in various industrial applications. Overall, ethyl 2-phenylhexanoate is a versatile compound with a wide range of uses in different industries.

Upstream product

• 19754-39-3 2.2-Dichlor-hexansaeure-ethlyester 
• 3220-49-3 phenyl copper 
• 109-65-9 1-bromo-butane 
• 101-97-3 Ethyl 2-phenylethanoate 
• 109-72-8 n-butyllithium 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 122-56-5 tributyl borane 
• 615-96-3 Ethyl 2-bromohexanoate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 2901-15-7 ethyl 2-butyl-2-phenylhaxanoate 
• 25755-73-1 2-benzene-2-butylethanol 

Relevant articles and documents

Deoxygenative α-alkylation and α-arylation of 1,2-dicarbonyls

Construction of C-C bonds at the α-carbon is a challenging but synthetically indispensable approach to α-branched carbonyl motifs that are widely represented among drugs, natural products, and synthetic intermediates. Here, we describe a simple approach to generation of boron enolates in the absence of strong bases that allows for introduction of both α-alkyl and α-aryl groups in a reaction of readily accessible 1,2-dicarbonyls and organoboranes. Obviation of unselective, strongly basic and nucleophilic reagents permits carrying out the reaction in the presence of electrophiles that intercept the intermediate boron enolates, resulting in two new α-C-C bonds in a tricomponent process. This journal is

Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: Synthesis of chiral benzofuranones

Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.

Ni-catalyzed mild arylation of α-halocarbonyl compounds with arylboronic acids

A simple yet powerful Ni catalyst can be used to promote direct arylations of α-halocarbonyl compounds, including a range of esters, amides, and ketones, with various arylboronic acids under mild conditions. The method tolerates β-hydrogens and functional groups in the substrates and offers reactivity and selectivity profiles that are complementary to those found in the well-established Buchwald-Hartwig approach.