29056-06-2

Usage

Uses

4-BUTOXYPHENYLACETIC ACID METHYL ESTER is used in Chemistry Research:
As a synthetic, organic compound, 4-BUTOXYPHENYLACETIC ACID METHYL ESTER is employed in chemistry research for its unique structural properties and potential applications in various chemical reactions and processes.
4-BUTOXYPHENYLACETIC ACID METHYL ESTER is used in Specialty Compound Catalogs:
This chemical is also found in specialty compound catalogs, where it is made available for researchers and professionals in the field of synthetic chemistry to explore its potential uses and properties further.

Upstream product

• 67-56-1 methanol 
• 109-65-9 1-bromo-butane 
• 156-38-7 4-hydroxyphenylacetate 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 

Downstream Products

• 581072-20-0 2-(4-butoxy-phenyl)-butyric acid methyl ester 
• 110319-79-4 N-hydroxy-N-methyl-2-(4-butoxyphenyl)propionamide 
• 3585-71-5 2-(4-butoxy)phenylpropionic acid 
• 3413-59-0 p-butoxyphenylacetamide 
• 4547-57-3 4-butoxyphenylacetic acid 
• 60003-47-6 4-butoxyphenylacetic acid chloride 
• 89790-00-1 N,N-dimethyl-p-butoxyphenylacetamide 
• 89789-99-1 2-(4-Butoxy-phenyl)-N-methyl-acetamide 
• 110319-87-4 methyl 2-(4-butoxyphenyl)propionate 

Relevant academic research and scientific papers

Oxime Carbamate-Discovery of a series of novel FAAH inhibitors

A series of novel oxime carbamates have been identified as potent inhibitors of the key regulatory enzyme of the endocannabinoid signaling system, fatty acid amide hydrolase (FAAH). In this Letter, the rationale behind the discovery and the biological evaluations of this novel class of FAAH inhibitors are presented. Both in vitro and in vivo results of selected targets are discussed, along with inhibition kinetics and molecular modeling studies.1.

PIPERAZINE AND PIPERIDINE MGLUR5 POTENTIATORS

Compounds of Formula I or pharmaceutically acceptable salts or solvates thereof, wherein A, B, D, Ar1, Ar2, R2, R3, R4, a, m and n are defined in the specification, methods for the use thereof, processes for making and pharmaceutical compositions containing the same.

1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof

The invention relates to combinatorial libraries containing two or more novel piperidine-3-carboxamide derivative compounds, methods of preparing the piperidine-3-carboxamide derivative compounds and piperidine-3-carboxamide derivative compounds bound to a resin

In Vivo Characterization of Hydroxamic Acid Inhibitors of 5-Lipoxygenase

The hydroxamic acid functionality can be incorporated into simple molecules to produce potent inhibitors of 5-lipoxygenase.The ability of many of these hydroxamates to inhibit leukotriene synthesis in vivo has been measured directly with a rat peritoneal anaphylaxis model.Despite their potent enzyme inhibitory activity in vitro, many orally dosed hydroxamic acids only weakly inhibited leukotriene synthesis in vivo.This discrepancy is attributable at least in part to the rapid metabolism of hydroxamates to the corresponding carboxylic acids, which are inactive against the enzyme.A study of the structural features that affect this metabolism revealed that 2-arylpropionohydroxamic acids are relatively resistant to metabolic hydrolysis.Several members of this class of hydroxamates are described that are orally active inhibitors of leukotriene synthesis.

Design of Inhibitors from the Three-Dimensional Structure of Alcohol Dehydrogenase. Chemical Synthesis and Enzymatic Properties

Inhibitors of liver alcohol dehydrogenase were designed from the three-dimensional structure of the enzyme.The ligand to the catalytic zinc ion is an amide group or, better, a formamide group.With the latter function, a hydrogen bond between the NH group and the hydroxyl group of Ser-48 may be formed.The hydrophobic substrate binding site brings structural restraints. α-ω bifunctional molecules show good inhibitory properties possibly due to the interactions with polar residues at the entrance of the substrate binding site.