29071-93-0

Usage

InChI:InChI=1/C7H12N2O3/c1-7(2)5(11)9(3-4-10)6(12)8-7/h10H,3-4H2,1-2H3,(H,8,12)

Upstream product

• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 
• 540-51-2 2-bromoethanol 

Downstream Products

• 53066-53-8 3-(2'-chloroethyl)-5, 5-dimethylhydantoin 

Relevant academic research and scientific papers

Synthesis of zwitterionic N-chlorohydantoins for antibacterial applications

Two novel zwitterionic N-chlorohydantoin biocides, containing an N-chlorohydantoin unit and a sulfobetaine unit or a carboxybetaine unit, were chemically synthesized and characterized. Using the quaternary ammonium N-chlorohydantoin as control, the antibacterial activity of synthetic zwitterionic N-chlorohydantoins was challenged and the antibacterial data showed that carboxybetaine N-chlorohydantoin exhibited distinctively higher biocidal efficacy than QA counterpart, while sulfobetaine N-chlorohydantoin displayed slightly inferior antimicrobial efficacy. Our results may inspire further exploration of more zwitterionic N-chlorohydantoin analogs for antibacterial application.

Bifunctional bactericide containing double bond, quaternary ammonium salt and halamine, and preparation method and application thereof

The invention relates to a bifunctional bactericide containing a double bond, a quaternary ammonium salt and halamine, and a preparation method and application thereof. The bactericide carries a C-C double bond and sterilizing bifunctional groups consisting of halamine and quaternary ammonium salt. The preparation method comprises the following steps: preparing 3-hydroxyalkyl-5,5-dimethylhydantoin at first, then carrying out a halogenation reaction to produce 3-haloalkyl-5,5-dimethylhydantoin, subjecting 3-haloalkyl-5,5-dimethylhydantoin and (dihydroxyamino)hydroxyacrylate to a quaternization reaction, and carrying out treatment by using a halogenation reagent. The bactericide provided by the invention is used through formation of a bactericidal coating on the surface of a material, wherein the bactericidal coating has a thickness of 5 nanometers to 5 micrometers. The bactericide provided by the invention forms the solid bactericidal coating through reaction on the surface of a material, is small in toxicity, wide in a bactericidal scope, long-lasting in bactericidal performance, high in bactericidal efficiency and safe to human beings, and can form the bactericidal coating on the surface of the material in a plurality of manners.