290825-97-7

Upstream product

• 108-94-1 cyclohexanone 
• 10424-93-8 N'-cyclohexylidene-N,N-dimethyl-hydrazine 
• 38002-45-8 3-bromo-1-(trimethylsilyl)-1-propyne 

Downstream Products

• 1323770-18-8 C₁₉H₂₀O₂ 
• 1323770-73-5 C₁₉H₁₇⁽²⁾H₃O₂ 
• 19823-75-7 2-(2-propynyl)cyclohexanone 
• 93026-61-0 1-benzyl-2-methyl-4,5,6,7-tetrahydro-1H-indole 

Relevant academic research and scientific papers

Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes

Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted β-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.

Gold-catalyzed 1,3-acyloxy migration/5-exo-dig cyclization/1,5-acyl migration of diynyl esters

Working three shifts: Polyconjugated δ-diketones are formed stereoselectively in high yields by the gold-catalyzed rearrangement of 1,6-diyn-3-yl esters. This cascade involves a 1,3-sigmatropic acyloxy shift, a 5-exo-dig cyclization of the resulting allenyne, and an unprecedented 1,5-sigmatropic shift of an acyl fragment. The usefulness of the products was shown by an efficient acid-catalyzed transformation into a complex polycyclic framework. Copyright