93026-61-0

Basic information

• Product Name: 1-BENZYL-2-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE
• Synonyms: 1-BENZYL-2-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE
• CAS NO: 93026-61-0
• Molecular Formula: C₁₆H₁₉N
• Molecular Weight: 225.33
• Mol File: 93026-61-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BENZYL-2-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-2-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE(93026-61-0)
• EPA Substance Registry System: 1-BENZYL-2-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE(93026-61-0)

Safety Data

• Hazardous Substances Data: 93026-61-0(Hazardous Substances Data)

Upstream product

• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 100-46-9 benzylamine 
• 513-31-5 2-bromoallyl bromide 
• 4471-09-4 N-benzylcyclohexylimine 
• 108-94-1 cyclohexanone 
• 290825-97-7 2-(3-trimethylsilyl-prop-2-ynyl)-cyclohexanone 
• 19823-75-7 2-(2-propynyl)cyclohexanone 
• 129286-74-4 (+/-)-N,N-dibenzylalaninal 
• 53626-84-9 2-(2-bromo-2-propen-1-yl)cyclohexanone 
• 17392-07-3 2-(2-chloroprop-2-enyl)cyclohexanone 
• 86953-53-9 Benzyl-[2-(2-bromo-allyl)-cyclohex-(Z)-ylidene]-amine 

Relevant articles and documents

Self-assembled coordination thioether silver(I) macrocyclic complexes for homogeneous catalysis

The bis-ortho-thioether 9,10-bis[(o-methylthio)phenyl]anthracene was synthesized as a syn-atropisomer, as revealed by X-ray diffraction. This alkylaryl thioether ligand (L) formed different macrocyclic complexes by coordination with silver(I) salts depending on the nature of the anion: M2L2 for AgOTf and AgOTFA, M6L4 for AgNO3. A discrete M2L complex was obtained in the presence of bulky PPh3AgOTf. These silver(I) complexes adopted similar structures in solution and in the solid state. As each sulfur atom in the ligand is prochiral, macrocycles L2M2 were obtained as mixtures of diastereoisomers, depending on the configurations of the sulfur atoms coordinated to silver cations. The X-ray structures of the two L2·(AgOTf)2 stereoisomers highlighted their different geometry. The catalytic activity of all silver(I) complexes was effective under homogeneous conditions in two tandem addition/cycloisomerization of alkynes using 0.5-1 mol % of catalytic loading.

Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes

Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted β-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.

A versatile synthesis of polysubstituted pyrroles

The aldol products formed by the reaction between α-(N-benzyl or N-Cbz)amino aldehydes and lithium enolates of various ketones, were subjected to hydrogenolysis to give polysubstituted pyrroles in good yields (50-91%). The scope and limitations of this me