290833-45-3Relevant academic research and scientific papers
Preparation of titanated alkoxyallenes from 3-alkoxy-2-propyn-1-yl carbonates and (η2-propene)Ti(O-i-Pr)2 as an efficient ester homoaldol equivalent
Hanazawa, Takeshi,Okamoto, Sentaro,Sato, Fumie
, p. 2369 - 2371 (2007/10/03)
(equation presented) 3-Alkoxy-2-propyn-1-yl carbonates (2) react with a divalent titanium reagent (η2-propene)Ti(O-i-Pr)2 to afford titanated alkoxyallenes 1 which, in turn, react with aldehydes regiospecifically to provide the corresponding γ-addition products in good to excellent yields, thus affording a convenient method for synthesizing γ-hydroxy esters 3 and/or γ-butyrolactones 4.
