2909-52-6

Basic information

• Product Name: BROMOFORM-D
• Synonyms: BROMOFORM-D;tribromo(2H)methane;BROMOFORM, 5000MG, NEAT;BROMOFORM-D, 99 ATOM % D;tribromomethane-d;Bromoform-D >99.5 Atom % D;BROMOFORM-D, 99 ATOM% D, STABILIZED, FOR NMR;Bromoform-d,for NMR,99 atom% D, stabilized
• CAS NO: 2909-52-6
• Molecular Formula: CHBr₃
• Molecular Weight: 253.74
• EINECS: 220-823-0
• Mol File: 2909-52-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 8 °C
• Boiling Point: 136.5 °C(lit.)
• Flash Point: 44°C
• Appearance: /
• Density: 2.906 g/mL at 25 °C(lit.)
• Vapor Pressure: 5.17mmHg at 25°C
• Refractive Index: n20/D 1.5956(lit.)
• CAS DataBase Reference: BROMOFORM-D(CAS DataBase Reference)
• NIST Chemistry Reference: BROMOFORM-D(2909-52-6)
• EPA Substance Registry System: BROMOFORM-D(2909-52-6)

Safety Data

• Hazard Codes: T,N
• Statements: 23-36/38-51/53-22
• Safety Statements: 28-45-61-26
• RIDADR: UN 2515 6.1/PG 3
• Hazardous Substances Data: 2909-52-6(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless liquid

Uses

Bromoform-d (CAS# 2909-52-6) is a useful isotopically labeled research compound.

InChI:InChI=1/CHBr3/c2-1(3)4/h1H

Upstream product

• 115-17-3 bromal 
• 18142-75-1 trimethyl-tribromomethyl-silane 
• 75-96-7 tribromoacetic acid 
• 81193-49-9 butyl-di-t-butylbromophosphonium tribromomethanid 
• 865-49-6 chloroform-d1 
• 67-64-1 acetone 
• 75-25-2 Bromoform 

Downstream Products

• 120156-95-8 IrBr(CO)(P(C₆H₅)3)2(SC(CN)C(CN)S) 

Relevant articles and documents

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Kinetic Isotope Effects for Proton Abstraction from Methanol by Polyhalogenomethyl Carbanions. Cleavage of Me3SiCHX2 and Me3SiCX3 by Base in Methanol.

The carbanions XxH(3-x)C- (X=Cl or Br; x=2 or 3) generated by base cleavage of Me3SiCH(3-x)Xx (or some related compounds) in MeOH, show a kinetic isotope kH/kD of ca. 1.1 in proton abstraction from methanol, as given by the product ratio XxH(3-x)CH/XxH(3-x)CD observed for reaction in MeOH-MeOD (1:1) at ca. 21 deg C.The low value of the isotope effect is attributed to the fact that the free electron pair in the carbanion is localized on the carbon centre; carbanions derived from acids of acidities comparable with those of X3CH and X2CH2 but in which the electron pair is conjugatively delocalized, show much larger isotope effects.

1-BROMOBICYCLOBUTANES AND STRONG BASES: PRODUCTS AND MECHANISM

Treatment of the bromobicyclobutanes 4a - c with LDA led to the formation of the 1,2,3-butatrienes 6 which were isomerized by excess base to the alkynes 8.Reaction of 4c with LDA afforded 8d, indicating that bicyclobut-1(3)-ene 5 was not an intermediate.