29097-01-6

Upstream product

• 100-63-0 phenylhydrazine 
• 67-56-1 methanol 
• 5334-43-0 5-Amino-4-cyano-1-phenylpyrazole 
• 1187-21-9 methyl 2-cyano-3-aminoacrylate 

Downstream Products

• 847021-81-2 methyl 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxylate 
• 847021-83-4 methyl 5-(2-formyl-1H-pyrrol-1-yl)-1-phenyl-1H-pyrazole-4-carboxylate 
• 847021-86-7 5-(2-formyl-1H-pyrrol-1-yl)-1-phenyl-1H-pyrazole-4-carboxylic acid 
• 1268626-50-1 C₄₀H₄₃N₁₇O₅ 

Relevant academic research and scientific papers

Synthesis and Biological Activity of Amide Compounds Containing Pyrazole Mandelic Acid Groups

A series of novel mandelic acid pyrazole amide compounds were synthesized and characterized. Moreover, their antiviral activities against tobacco mosaic virus were evaluated. The bioassay results indicated that as-prepared compounds showed antiviral activity against tobacco mosaic virus at a concentration of 500?g/mL. The curative activity of compound 4g is 59.5%, which was comparable with positive control (Ningnanmycin, 61.0%). The inactivation activity of the compound 4l exhibited 80.1%, which was higher than that of Ningnanmycin (75.0%), and its protective activity was 88.7%, which is comparable with that of Ningnanmycin (90.7%).

5-Aminopyrrazole deriv. or method of manufacturing the same

PROBLEM TO BE SOLVED: To provide a method for producing a 5-aminopyrazole derivative at a reduced production cost and in high yields. SOLUTION: The method for producing a 5-aminopyrazole derivative or a salt thereof includes performing the following steps (a) and (b) in the order: (a) the step of deriving an intermediate by reacting a compound having a specified structure or a salt thereof with an active methylene compound having a specified structure; and (b) the step of obtaining the 5-aminopyrazole derivative or a salt thereof by reacting the intermediate with a hydrazine derivative. COPYRIGHT: (C)2011,JPOandINPIT