292045-48-8

Basic information

• Product Name: (6-([4-(imidazol-1-ylcarbonyl)phenylamino]methyl)-4-oxo-3,4-dihydro-pteridin-2-yl)-carbamic acid 2-trimethylsilylethyl ester
• Synonyms: (6-([4-(imidazol-1-ylcarbonyl)phenylamino]methyl)-4-oxo-3,4-dihydro-pteridin-2-yl)-carbamic acid 2-trimethylsilylethyl ester
• CAS NO: 292045-48-8
• Molecular Weight: 506.596
• Mol File: 292045-48-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (6-([4-(imidazol-1-ylcarbonyl)phenylamino]methyl)-4-oxo-3,4-dihydro-pteridin-2-yl)-carbamic acid 2-trimethylsilylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (6-([4-(imidazol-1-ylcarbonyl)phenylamino]methyl)-4-oxo-3,4-dihydro-pteridin-2-yl)-carbamic acid 2-trimethylsilylethyl ester(292045-48-8)
• EPA Substance Registry System: (6-([4-(imidazol-1-ylcarbonyl)phenylamino]methyl)-4-oxo-3,4-dihydro-pteridin-2-yl)-carbamic acid 2-trimethylsilylethyl ester(292045-48-8)

Safety Data

• Hazardous Substances Data: 292045-48-8(Hazardous Substances Data)

Upstream product

• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 119-24-4 Pteroic acid 
• 119-24-4 pteroic acid 
• 530-62-1 1,1'-carbonyldiimidazole 
• 59-30-3 folic acid 

Downstream Products

• 292045-47-7 α-[2-(trimethylsilyl)ethoxy]-2-N-[2-(trimethylsilyl)ethoxycarbonyl]folic acid 
• 292045-57-9 5-[6-[γ-[α-[2-(trimethylsilyl)ethoxy]-2-N-[2-(trimethylsilyl)ethoxycarbonyl]folyl]amino]hexylcarbamoyl]-1-(2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)uracil 
• 292045-54-6 1-(2-deoxy-2-methylene-β-D-erythro-pentofuranosyl)-4-N-[γ-[α-[2-(trimethylsilyl)ethoxy]-2-N-[2-(trimethylsilyl)ethoxycarbonyl]folyl]]cytosine 

Relevant articles and documents

Regioselective synthesis of folic acid conjugates from diether-type archaeal lipid analogues

A regioselective access to both α- and γ-folic acid conjugates derived from archaeal lipid analogues is described. The synthetic approach is based on conveniently protected glutamates that led first to α- and γ-glutamate derivatives. The final reconstruct

PROCESS FOR PRODUCING FOLIC ACID DERIVATIVE

This invention provides a process for efficient production of folic acid derivatives suitable for forming conjugates of anticancer drug with folic acid. It discloses a process comprising a step of reacting 2-amino-protected pteroylimidazole with 3-lower a